1523-17-7

Basic information

• Product Name: (4-bromophenyl) benzoate
• Synonyms: (4-bromophenyl) benzoate
• CAS NO: 1523-17-7
• Molecular Formula: C₁₃H₉BrO₂
• Molecular Weight: 277.11
• Mol File: 1523-17-7.mol
• Article Data: 43

Chemical Properties

• Boiling Point: 359.4°Cat760mmHg
• Flash Point: 171.1°C
• Appearance: /
• Density: 1.465g/cm³
• Vapor Pressure: 2.39E-05mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: (4-bromophenyl) benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromophenyl) benzoate(1523-17-7)
• EPA Substance Registry System: (4-bromophenyl) benzoate(1523-17-7)

Safety Data

• Hazardous Substances Data: 1523-17-7(Hazardous Substances Data)

Usage

Description

(4-bromophenyl) benzoate is a chemical compound that features a benzene ring with a benzoate ester group at one end and a bromine atom attached to the phenyl ring. It is known for its ability to react with various chemicals, making it a versatile starting material for creating a wide range of organic molecules.

Uses

Used in Pharmaceutical and Agrochemical Industries:
(4-bromophenyl) benzoate is used as a building block in the synthesis of various organic compounds, particularly in the pharmaceutical and agrochemical industries. Its versatility allows for the creation of different compounds with potential applications in these fields.
Used in Fragrance and Flavoring Production:
(4-bromophenyl) benzoate is also utilized as an intermediate in the production of fragrances and flavorings. Its chemical structure enables it to contribute to the development of new and unique scents and tastes.
Used in Organic Chemistry Research:
As a starting material, (4-bromophenyl) benzoate is valuable in organic chemistry research. It can be used to explore new reactions, such as esterification and nucleophilic substitution, leading to the discovery of novel compounds with potential applications in various industries.

InChI:InChI=1/C13H9BrO2/c14-11-6-8-12(9-7-11)16-13(15)10-4-2-1-3-5-10/h1-9H

Upstream product

• 93-99-2 benzoic acid phenyl ester 
• 106-41-2 4-bromo-phenol 
• 98-88-4 benzoyl chloride 
• 7003-65-8 sodium 4-bromophenoxide 
• 98-07-7 Benzotrichlorid 
• 65-85-0 benzoic acid 
• 618-32-6 Benzoyl bromide 
• 67963-68-2 t-butyldimethylsilyl-4-bromophenol 
• 7726-95-6 bromine 
• 7553-56-2 iodine 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 93-89-0 benzoic acid ethyl ester 
• 848417-68-5 3,6-dibenzoyloxy-1,2-pyridazine 

Downstream Products

• 55082-33-2 5-bromo-2-hydroxybenzophenone 
• 88681-66-7 Benzoic acid 4-((Z)-2-acetylamino-2-carboxy-vinyl)-phenyl ester 
• 532-32-1 sodium benzoate 
• 7003-65-8 sodium 4-bromophenoxide 
• 93-89-0 benzoic acid ethyl ester 
• 2042-41-3 p-bromophenoxide ion 
• 106-41-2 4-bromo-phenol 
• 69918-18-9 (E)-(5-bromo-2-hydroxyphenyl)(phenyl)methanone oxime 
• 1295567-90-6 4-bromo-2-{α-[1-(4-bromophenyl)benzoimidazol-2-yl]benzyl}phenol 
• 1295567-91-7 4-bromo-2-{α-[1-(4-dimethylaminophenyl)benzoimidazol-2-yl]benzyl}phenol 
• 1295567-92-8 C₂₆H₁₉BrN₂O 
• 1295567-93-9 C₂₄H₁₇BrN₂O₂ 
• 1295567-94-0 4-bromo-2-{α-[1-(2-thienyl)benzoimidazol-2-yl]-benzyl}phenol 
• 1295567-95-1 C₂₆H₁₈BrN₃O₃ 

Relevant articles and documents

Isolation of an inclusion complex of naphthol and its benzoate as an intermediate in the solvent-free benzoylation reaction of naphthol

A study was performed on isolation of an inclusion complex of naphthol and its benzoate as an intermediate in the solvent-free benzoylation reaction of naphthol. Solvent-free benzoylation reactions were carried out by heating a stirred mixture of phenols or naphthols and benzoyl chloride. The structure of the 2 : 1 inclusion complex of 2,3 naphthalenediol and its p-methylbenzoate was studied by X-ray analysis.

Hydrogen-bond-assisted transition-metal-free catalytic transformation of amides to esters

The amide C-N cleavage has drawn a broad interest in synthetic chemistry, biological process and pharmaceutical industry. Transition-metal, luxury ligand or excess base were always vital to the transformation. Here, we developed a transition-metal-free hydrogen-bond-assisted esterification of amides with only catalytic amount of base. The proposed crucial role of hydrogen bonding for assisting esterification was supported by control experiments, density functional theory (DFT) calculations and kinetic studies. Besides broad substrate scopes and excellent functional groups tolerance, this base-catalyzed protocol complements the conventional transition-metal-catalyzed esterification of amides and provides a new pathway to catalytic cleavage of amide C-N bonds for organic synthesis and pharmaceutical industry. [Figure not available: see fulltext.]

N,O-Benzyl Protection of Structurally Varied Amines and Phenols Using Wells-Dawson Heteropolyacid Catalyst

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