152459-75-1

Basic information

• Product Name: 2-Pyrimidinamine, N-(3-nitrophenyl)-4-(3-pyridinyl)-
• CAS NO: 152459-75-1
• Molecular Formula: C15H11N5O2
• Molecular Weight: 293.285
• Mol File: 152459-75-1.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-Pyrimidinamine, N-(3-nitrophenyl)-4-(3-pyridinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrimidinamine, N-(3-nitrophenyl)-4-(3-pyridinyl)-(152459-75-1)
• EPA Substance Registry System: 2-Pyrimidinamine, N-(3-nitrophenyl)-4-(3-pyridinyl)-(152459-75-1)

Safety Data

• Hazardous Substances Data: 152459-75-1(Hazardous Substances Data)

Upstream product

• 142992-99-2 N-(3-nitro-phenyl)-guanidine nitrate 
• 55314-16-4 (E)-3-(dimethylamino)-1-(pyridin-3-yl)prop-2-en-1-one 
• 350-03-8 methyl-3-pyridylketone 
• 24067-37-6 N-(3-Nitrophenyl)guanidine 

Downstream Products

• 152460-06-5 N-(3-aminophenyl)-4-(pyridin-3-yl)-2-pyrimidine-amine 

Relevant articles and documents

Anti-hepatitis B application of conjugate

The invention mainly provides application of a conjugate in preparation of a medicine for treating hepatitis B virus infection. The conjugate is obtained by connecting formyl in an orlistat structureto amino in a phenylaminopyrimidine compound structure,

N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof

The present invention relates to an N-phenyl-2-pyrimidine-amine derivative showing a superior effect on lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or acute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer, or cervical cancer, etc. of warm-blooded animals and its salt. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various diseases, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.

N-PHENYL-2-PYRIMIDINE-AMINE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF

The present invention relates to an N-Phenyl-2-pyrimidine-aminine derivative showing a superior effect on lung cancer, gastric cancer, colon cancer, pancreatic cancer, hepatoma, prostatic cancer, breast cancer, chronic or accute leukemia, hematologic malignancy, encephalophyma, bladder cancer, rectal cancer or cervical cancer, etc. of warm blooded animals and its salt. The present invention also relates to a process for preparing the compound, and to a pharmaceutical composition for the treatment of the above various disease, which comprises an effective amount of the compound as an active ingredient together with pharmaceutically acceptable inert carriers.