152706-23-5 Usage
Description
(S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL is a chemical compound belonging to the aziridine family, commonly utilized in organic synthesis. As a chiral compound with a non-superimposable mirror image, it serves as a crucial building block for the preparation of various pharmaceuticals and biologically active molecules. The trityl group, acting as a protecting group for alcohols, is attached to the nitrogen atom of the aziridine ring, making (S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL a valuable intermediate in organic chemistry. (S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL holds potential for use in the development of new drugs and the creation of complex organic molecules for a wide range of applications.
Uses
Used in Pharmaceutical Industry:
(S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL is used as a building block for the synthesis of various pharmaceuticals due to its unique structure and reactivity. Its chiral nature allows for the creation of enantiomerically pure compounds, which are essential in the development of effective and selective medications.
Used in Organic Synthesis:
In the field of organic chemistry, (S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL is used as an intermediate for the preparation of complex organic molecules. Its trityl group provides a protective function for alcohols, facilitating the synthesis of target molecules with greater ease and precision.
Used in Drug Development:
(S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL holds potential for use in the development of new drugs, particularly in the creation of biologically active molecules. Its unique structure and properties make it a valuable tool in the design and synthesis of novel therapeutic agents.
Used in Research and Development:
(S)-(1-TRITYLAZIRIDIN-2-YL)METHANOL is also utilized in research and development settings, where it can be employed to study the properties and reactivity of aziridine-based compounds. This knowledge can be applied to the design of new synthetic routes and the development of innovative applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 152706-23-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,7,0 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 152706-23:
(8*1)+(7*5)+(6*2)+(5*7)+(4*0)+(3*6)+(2*2)+(1*3)=115
115 % 10 = 5
So 152706-23-5 is a valid CAS Registry Number.
152706-23-5Relevant articles and documents
COVALENT RAS INHIBITORS AND USES THEREOF
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Page/Page column 272-273, (2021/06/04)
The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.
N-Trityl-aziridinyl alcohols as highly efficient chiral catalysts in asymmetric additions of organozinc species to aldehydes
Jarzyski, Szymon,Lesniak, Stanislaw,Pieczonka, Adam M.,Rachwalski, Michal
, p. 35 - 40 (2015/03/03)
A synthetic route leading to a series of new chiral catalysts containing the N-trityl-aziridine moiety and a primary and a secondary hydroxyl group as nucleophilic centers is described. All the new compounds have been tested as chiral catalysts in the enantioselective addition of diethylzinc and phenylethynylzinc to aryl and alkyl aldehydes, yielding the corresponding chiral alcohols in high chemical yields (up to 96%) and with excellent ee's of ca. 90%. The influence of the stereogenic centers located at the carbon atom bonded with the hydroxyl moiety and on the carbon of the aziridine ring on the stereochemistry of the addition reactions is also discussed.
Asymmetrie total syntheses of (-)-renieramycin M and G and (-)-jorumycin using aziridine as a lynchpin
Wu, Yan-Chao,Zhu, Jieping
supporting information; experimental part, p. 5558 - 5561 (2010/02/28)
"Chemical Equation Presented" By exploring the triple reactivity of two aziridines and double nucleophilicity of two aromatics, convergent and versatile syntheses of the above four natural products were developed.
