152832-96-7

Basic information

• Product Name: p-6-O⁶-[(hydroxymethyl)benzyl]guanine
• Synonyms: p-6-O⁶-[(hydroxymethyl)benzyl]guanine
• CAS NO: 152832-96-7
• Molecular Weight: 271.279
• Mol File: 152832-96-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-6-O⁶-[(hydroxymethyl)benzyl]guanine(CAS DataBase Reference)
• NIST Chemistry Reference: p-6-O⁶-[(hydroxymethyl)benzyl]guanine(152832-96-7)
• EPA Substance Registry System: p-6-O⁶-[(hydroxymethyl)benzyl]guanine(152832-96-7)

Safety Data

• Hazardous Substances Data: 152832-96-7(Hazardous Substances Data)

Upstream product

• 589-29-7 p-xylylene glycol 
• 10310-21-1 2-Amino-6-chloropurin 

Downstream Products

• 868682-30-8 N^2,9-bis-(p-anisyldiphenylmethyl)-O⁶-[4-(2-fluoroethoxymethyl)benzyl]guanine 
• 868682-29-5 N^2,9-bis-(p-anisyldiphenylmethyl)-O⁶-[4-(hydroxymethyl)benzyl]guanine 
• 868682-28-4 N^2,9-bis-(p-anisyldiphenylmethyl)-O⁶-(4-formylbenzyl)guanine 
• 152832-97-8 O⁶-(p-formylbenzyl)guanine 

Relevant articles and documents

Synthesis and preliminary biological evaluation of O6-[4-(2- [18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy

A novel fluorine-18-labeled O6-benzylguanine (O6-BG) derivative, O6-[4-(2-[18F]fluoroethoxymethyl)benzyl] guanine (O6-[18F]FEMBG, [18F]1), has been synthesized for evaluation as

Substituted O6-benzylguanine derivatives and their inactivation of human O6-alkylguanine-DNA alkyltransferase

Several new O6-benzylguanine analogs bearing increasingly bulky substituent groups on the benzene ring or at position 9 were tested for their ability to inactivate the human DNA repair protein, O6-alkylguanine-DNA alkyltransferase. S