152971-88-5

Basic information

• Product Name: Isoquinoline, 1,2,3,4-tetrahydro-1-(1-methylethyl)-, (S)- (9CI)
• Synonyms: Isoquinoline, 1,2,3,4-tetrahydro-1-(1-methylethyl)-, (S)- (9CI);(S)-1-Isopropyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 152971-88-5
• Molecular Formula: C12H17N
• Molecular Weight: 175.27008
• Product Categories: ISOPROPYL
• Mol File: 152971-88-5.mol
• Article Data: 23

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isoquinoline, 1,2,3,4-tetrahydro-1-(1-methylethyl)-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Isoquinoline, 1,2,3,4-tetrahydro-1-(1-methylethyl)-, (S)- (9CI)(152971-88-5)
• EPA Substance Registry System: Isoquinoline, 1,2,3,4-tetrahydro-1-(1-methylethyl)-, (S)- (9CI)(152971-88-5)

Safety Data

• Hazardous Substances Data: 152971-88-5(Hazardous Substances Data)

Upstream product

• 75-30-9 2-iodo-propane 
• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 71611-83-1 1-isopropyl-3,4-dihydroisoquinoline 
• 54923-45-4 dimethyl-1-isoquinolylmethanol 
• 78702-57-5 2-bis(dimethylamino)phosphinoyl-1-isopropyl-1,2,3,4-tetrahydroisoquinoline 
• 142387-75-5 [2-(2-Bromo-phenyl)-ethyl]-[2-methyl-prop-(E)-ylidene]-amine 
• 164020-61-5 2-bromo-N-(2-methylpropylidene)benzeneethanamine 
• 85838-87-5 N-(2-methylpropylidene)benzeneethanamine 
• 1068-55-9 isopropylmagnesium chloride 
• 927406-87-9 2-(4,5-dihydro-thiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline 
• 103-63-9 1-phenyl-2-bromoethane 
• 78702-53-1 2-bis(dimethylamino)phosphinoyl-1,2,3,4-tetrahydroisoquinoline 
• 76068-81-0 1-(3,4-dihydroisoquinolin-2(1H)-yl)-2,2-dimethylpropan-1-one 
• 77796-20-4 1-isopropyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 1721-93-3 1-methylisoquinoline 
• 20922-03-6 1-(propan-2-yl)isoquinoline 
• 4965-09-7 1-methyl-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

A through halogen bond activation isoquinoline asymmetric hydrogenation method

A through halogen bond activation isoquinoline asymmetric hydrogenation method, the catalyzing system is [...] complex, the activator is a halide. The reaction can be carried out under the following conditions, temperature: 25 - 100 °C; solvent: tetrahydr

A method catalyzed by iridium and used for bidirectional enantioselective synthesis of chiral tetrahydroisoquinoline

A method catalyzed by iridium and used for bidirectional enantioselective synthesis of chiral tetrahydroisoquinoline is provided. A catalysis system adopted by the method is a chiral diphosphine complex of iridium. By utilizing a single chiral source and

Identification of an Imine Reductase for Asymmetric Reduction of Bulky Dihydroisoquinolines

A new imine reductase from Stackebrandtia nassauensis (SnIR) was identified, which displayed over 25- to 1400-fold greater catalytic efficiency for 1-methyl-3,4-dihydroisoquinoline (1-Me DHIQ) compared to other imine reductases reported. Subsequently, an efficient SnIR-catalyzed process was developed by simply optimizing the amount of cosolvent, and up to 15 g L-1 1-Me DHIQ was converted completely without a feeding strategy. Furthermore, the reaction proceeded well for a panel of dihydroisoquinolines, affording the corresponding tetrahydroisoquinolines (mostly in S-configuration) in good yields (up to 81%) and with moderate to excellent enantioselectivities (up to 99% ee).