153042-86-5Relevant articles and documents
Medicinal foodstuffs. II. On the bioactive constituents of the tuber of Sagittaria trifolia L. (Kuwai, Alismataceae): Absolute stereostructures of trifoliones A, B, C, and D, sagittariosides a and b, and arabinothalictoside
Yoshikawa,Yoshizumi,Murakami,Matsuda,Yamahara,Murakami
, p. 492 - 499 (2007/10/03)
From the medicinal foodstuff 'kuwai', the tuber of Sagittaria trifolia L., four bioactive diterpene ketones, trifoliones A, B, C, and D, two diterpene glucosides, sagittariosides a and b, and a nitroethylphenol glycoside, arabinothalictoside, were isolated, together with six known diterpenes. Their absolute stereostructures were determined on the basis of chemical and physicochemical evidence which included the application of a modified Mosher's method and an exciton chirality method. Among the diterpene constituents, trifoliones A, B, C, and D exhibited inhibitory effects on the histamine release from rat mast cells induced by compound 48/80 and calcium ionophore A-23187.