153435-63-3 Usage
Description
2-(Tributylstannyl)pyrimidine is an organotin compound characterized by its clear colorless liquid appearance. It is a significant reagent in the field of organic synthesis, particularly for Stille coupling reactions, which are widely utilized in the creation of various complex organic molecules.
Uses
Used in Pharmaceutical Industry:
2-(Tributylstannyl)pyrimidine is used as a synthetic precursor for the development of 2-aminopyridine oxazolidinones. These compounds are recognized as potent and selective tankyrase (TNKS) inhibitors, playing a crucial role in the treatment of various diseases by targeting specific cellular pathways.
2-(Tributylstannyl)pyrimidine is also used as a synthetic precursor in the production of canagliflozin, a novel inhibitor for the sodium-dependent glucose cotransporter. 2-(Tributylstannyl)pyrimidine has potential applications in the management of diabetes by regulating glucose absorption in the body.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-(Tributylstannyl)pyrimidine is employed in the preparation of various (2-pyrimidyl)silanes. These silane compounds have diverse applications, including their use as coupling agents, adhesion promoters, and in the creation of materials with specific properties for various industries.
Overall, 2-(Tributylstannyl)pyrimidine is a versatile organotin compound with significant applications in the pharmaceutical and chemical synthesis industries, contributing to the development of innovative treatments and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 153435-63-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,4,3 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 153435-63:
(8*1)+(7*5)+(6*3)+(5*4)+(4*3)+(3*5)+(2*6)+(1*3)=123
123 % 10 = 3
So 153435-63-3 is a valid CAS Registry Number.
InChI:InChI=1/C4H3N2.3C4H9.Sn/c1-2-5-4-6-3-1;3*1-3-4-2;/h1-3H;3*1,3-4H2,2H3;/rC16H30N2Sn/c1-4-7-13-19(14-8-5-2,15-9-6-3)16-17-11-10-12-18-16/h10-12H,4-9,13-15H2,1-3H3
153435-63-3Relevant articles and documents
PYRAZINE DERIVATIVE AND APPLICATION THEREOF IN INHIBITING SHP2
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Paragraph 0129-0130, (2022/01/23)
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Phenanthroline compound and organic light emitting element comprising the same
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Paragraph 0071; 0072-0074, (2018/09/02)
The present invention relates to a phenanthroline compound and an organic electroluminescent device exhibiting excellent efficiency characteristics by including the compound in one or more organic layers. The phenanthroline compound is represented by chemical formula 1. In chemical formula 1, X_1 and X_2 are nitrogen, Ar is a chemical bond, a phenyl group, a naphthalene group, a biphenyl group, a pyridine group or a quinoline group, and L is a chemical bond, a phenyl group, a naphthalene group, a biphenyl group, a pyridine group, or a quinoline group.COPYRIGHT KIPO 2018
COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME
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Page/Page column 58; 77; 95, (2010/11/24)
The present invention provides compounds of formula (I) or compounds of formula (II) and pharmaceutically acceptable salts or solvates thereof. An objective of the present invention is to provide compounds having TGF2 inhibitory activity.