153439-89-5Relevant articles and documents
Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide
Veerapen, Natacha,Brigl, Manfred,Garg, Salil,Cerundolo, Vincenzo,Cox, Liam R.,Brenner, Michael B.,Besra, Gurdyal S.
scheme or table, p. 4288 - 4291 (2010/04/26)
We herein report a faster and less cumbersome synthesis of the biologically attractive, α-galactosyl ceramide (α-GalCer), known as KRN7000, and its analogues. More importantly, the use of a silicon tethered intramolecular glycosylation reaction gave easy
Efficient stereocontrolled glycosidation of secondary sugar hydroxyls by silicon tethered intramolecular glycosidation
Bols
, p. 10049 - 10060 (2007/10/02)
Dissaccharides containing 1,2-cis glycoside linkages were synthesized by an efficient stereocontrolled two step process involving a silicon tethering step, to a dimethylsilyl acetal followed by intramolecular glycosidation with N-iodosuccinimide in nitrom