153660-04-9

Basic information

• Product Name: 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER TRIETHYLAMMONIUM SALT
• Synonyms: RP-8-[(4-CHLOROPHENYL)THIO]-GUANOSINE-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE TRIETHYLAMINE;RP-8-PCPT-CGMPS;RP-8-PCPT-CGMPS SODIUM SALT;RP-8-PCPT-CGMPS, TEA;RP-8-P-CPT-CGMPS TRIETHYLAMINE;GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, 8-(4-CHLOROPHENYLTHIO)-, RP-ISOMER, TRIETHYLAMMONIUM SALT;8-(4-CHLOROPHENYLTHIO) GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, RP-ISOMER SODIUM SALT;8-(4-CHLOROPHENYLTHIO)GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE SODIUM SALT, RP-ISOMER
• CAS NO: 153660-04-9
• Molecular Formula: C22H30ClN6O6PS2
• Molecular Weight: 605.07
• Mol File: 153660-04-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: Not Available
• Appearance: white/solid
• Density: Not Available
• Storage Temp.: −20°C
• Solubility: H2O: 5 mg/mL
• CAS DataBase Reference: 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER TRIETHYLAMMONIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER TRIETHYLAMMONIUM SALT(153660-04-9)
• EPA Substance Registry System: 8-(4-CHLOROPHENYLTHIO)GUANOSINE 3',5'-CYCLIC MONOPHOSPHOTHIOATE, RP-ISOMER TRIETHYLAMMONIUM SALT(153660-04-9)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 153660-04-9(Hazardous Substances Data)

Usage

General Description

The chemical 8-(4-chlorophenylthio)guanosine 3',5'-cyclic monophosphothioate, RP-isomer triethylammonium salt is a compound that belongs to the class of cyclic nucleotide analogs and is used in research as a selective activator of the cAMP-dependent protein kinase (PKA). It is a potent and cell-permeable activator of PKA, which plays a key role in numerous cellular processes such as gene transcription, metabolism, and cell growth. The compound is often used in studies to understand the mechanisms of PKA activation and its downstream effects, as well as to investigate potential therapeutic applications in various diseases such as cancer, cardiovascular disorders, and neurological conditions. Its triethylammonium salt form improves its solubility and allows for better handling in experimental settings.