154105-64-3

Basic information

• Product Name: 4-Bromopyridine-3-carboxaldehyde
• Synonyms: 4-Bromopyridine-3-carboxaldehyde;4-Bromonicotinaldehyde;4-bromopyridine-3-carbaldehyde;4-Bromonicitinaldehyde;3-Pyridinecarboxaldehyde,4-broMo-
• CAS NO: 154105-64-3
• Molecular Formula: C₆H₄BrNO
• Molecular Weight: 186.00606
• EINECS: -0
• Product Categories: pharmacetical;Pyridine;Aldehyde;Organohalides
• Mol File: 154105-64-3.mol
• Article Data: 18

Chemical Properties

• Melting Point: 49-50°C
• Boiling Point: 263.334 °C at 760 mmHg
• Flash Point: 113.061 °C
• Appearance: yellow solid
• Density: 1.683 g/cm³
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.619
• PKA: 2.19±0.10(Predicted)
• CAS DataBase Reference: 4-Bromopyridine-3-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromopyridine-3-carboxaldehyde(154105-64-3)
• EPA Substance Registry System: 4-Bromopyridine-3-carboxaldehyde(154105-64-3)

Safety Data

• Hazardous Substances Data: 154105-64-3(Hazardous Substances Data)

Usage

General Description

4-Bromopyridine-3-carboxaldehyde is an organic chemical compound with the molecular formula C6H4BrNO. Its systematic name is 4-Bromopyridine-3-carbaldehyde and it belongs to the product categories of bromopyridines and aldehydes. 4-Bromopyridine-3-carboxaldehyde appears as a clear light yellow liquid and has a strong odor. Its most common applications span from organic synthesis to being used as an active pharmaceutical ingredient intermediate. It's advised to handle this chemical in a well-ventilated area while wearing appropriate personal protective equipment due to its potential corrosive nature when in contact with skin, eyes, respiratory, or digestive tracts. Generally, 4-bromopyridine-3-carboxaldehyde is classified as harmful and dangerous for the environment.

InChI:InChI=1/C6H4BrNO/c7-6-1-2-8-3-5(6)4-9/h1-4H

Upstream product

• 1120-87-2 4-bromopyridin 
• 68-12-2 N,N-dimethyl-formamide 
• 19524-06-2 4-bromopyridine hydrochloride 
• 500-22-1 3-pyridinecarboxaldehyde 
• 2591-86-8 N-Formylpiperidine 

Downstream Products

• 222167-67-1 4-Phenylethynyl-pyridine-3-carbaldehyde 
• 197007-87-7 (4-bromo-pyridin-3-yl)-methanol 
• 478149-07-4 methyl thieno[3,2-c]pyridine-2-carboxylate 
• 197007-88-8 4-bromo-3-pyridinemethanol benzyl ether 
• 253-45-2 [2,7]naphthyridine 
• 90230-26-5 3-phenyl-[2,7]naphthyridine 
• 222168-90-3 4-Phenylethynyl-pyridine-3-carbaldehyde oxime 
• 31482-18-5 pauridianthine 

Relevant articles and documents

trans-2,6-, 3,6- And 4,6-diaza-5,6,6a,7,8,12b-hexahydrobenzophenanthrene-10,11-diols as dopamine agonists

The title compounds were synthesized by replacing the thiophene moiety of A-86929(2a) with variously substituted pyridines. Dopamine D-1 and D-2 binding and adenylate cyclase assays indicate that 4,6-diaza compounds 15 are potent and selective full D1 agonists when R1 is H or a small substituent and R2=H, with D1 binding affinity and adenylate cyclase functional potency equivalent to that of A-86929(2a).

Five-membered azole heterocyclic compound and its preparation method, pharmaceutical composition and use thereof

The present invention relates to a five-membered azole heterocycle compound represented by the following general formula (I), a preparation method of the five-membered azole heterocycle compound, a drug composition of the five-membered azole heterocycle compound, and a use of the five-membered azole heterocycle compound in preparation of drugs for prevention or treatment of TGR5-mediated diseases. The formula (I) is represented by the instruction.

ARYL ETHER-BASE KINASE INHIBITORS

The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.