15416-91-8 Usage
Description
Farnesyl monophosphate is a member of the class of farnesyl phosphates and is the monophosphatr derivative of (2E,6E)-farnesol. It is a naturally occurring compound that plays a significant role in various biological processes.
Uses
1. Used in Pharmaceutical Industry:
Farnesyl monophosphate is used as a key intermediate in the synthesis of various pharmaceutical compounds, particularly those targeting cancer cells. Its unique structure allows for the development of drugs that can modulate cellular signaling pathways, potentially leading to the inhibition of tumor growth and progression.
2. Used in Flavor and Fragrance Industry:
Farnesyl monophosphate is used as a building block for the production of various fragrances and flavors. Its distinct chemical properties enable the creation of a wide range of scents and tastes, making it a valuable component in the development of new and innovative products.
3. Used in Cosmetic Industry:
Farnesyl monophosphate is utilized in the formulation of cosmetics due to its potential benefits for skin health. It may be incorporated into anti-aging products, as it could help promote cell regeneration and improve skin elasticity.
4. Used in Research and Development:
Farnesyl monophosphate serves as an important compound for scientific research, particularly in the fields of biochemistry and molecular biology. It is used to study the mechanisms of various cellular processes and to develop new therapeutic strategies for a range of diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 15416-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,1 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15416-91:
(7*1)+(6*5)+(5*4)+(4*1)+(3*6)+(2*9)+(1*1)=98
98 % 10 = 8
So 15416-91-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H27O4P/c1-13(2)7-5-8-14(3)9-6-10-15(4)11-12-19-20(16,17)18/h7,9,11H,5-6,8,10,12H2,1-4H3,(H2,16,17,18)/b14-9-,15-11-
15416-91-8Relevant articles and documents
Enzymatic synthesis of lipid II and analogues
Huang, Lin-Ya,Huang, Shih-Hsien,Chang, Ya-Chih,Cheng, Wei-Chieh,Cheng, Ting-Jen R.,Wong, Chi-Huey
, p. 8060 - 8065 (2014)
The emergence of antibiotic resistance has prompted active research in the development of antibiotics with new modes of action. Among all essential bacterial proteins, transglycosylase polymerizes lipid II into peptidoglycan and is one of the most favorable targets because of its vital role in peptidoglycan synthesis. Described in this study is a practical enzymatic method for the synthesis of lipid II, coupled with cofactor regeneration, to give the product in a 50-70 % yield. This development depends on two key steps: the overexpression of MraY for the synthesis of lipid I and the use of undecaprenol kinase for the preparation of polyprenol phosphates. This method was further applied to the synthesis of lipid II analogues. It was found that MraY and undecaprenol kinase can accept a wide range of lipids containing various lengths and configurations. The activity of lipid II analogues for bacterial transglycolase was also evaluated.
One-pot synthesis of organophosphate monoesters from alcohols
Lira, Lucas M.,Vasilev, Dimitar,Pilli, Ronaldo A.,Wessjohann, Ludger A.
, p. 1690 - 1692 (2013/04/10)
A one-pot procedure for the phosphorylation of alcohols provides the corresponding phosphate monoesters in improved yields. The protocol features the use of tetrabutylammonium hydrogen phosphate and trichloroacetonitrile, followed by purification of the crude product by flash chromatography on silica gel. The final step, cation exchange chromatography, affords the organophosphates as ammonium salts that are usually required for biochemical applications. The mechanism appears to be phosphate rather than alcohol activation by trichloroacetonitrile.
