154499-36-2

Basic information

• Product Name: 2-Oxazolidinone, 3-(2-methyl-1-oxo-2-propenyl)-4-phenyl-, (4S)-
• CAS NO: 154499-36-2
• Molecular Formula: C13H13NO3
• Molecular Weight: 231.251
• Mol File: 154499-36-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-(2-methyl-1-oxo-2-propenyl)-4-phenyl-, (4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-(2-methyl-1-oxo-2-propenyl)-4-phenyl-, (4S)-(154499-36-2)
• EPA Substance Registry System: 2-Oxazolidinone, 3-(2-methyl-1-oxo-2-propenyl)-4-phenyl-, (4S)-(154499-36-2)

Safety Data

• Hazardous Substances Data: 154499-36-2(Hazardous Substances Data)

Upstream product

• 79-41-4 poly(methacrylic acid) 
• 99395-88-7 (S)-4-phenyl-2-oxazolidinone 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 1257664-76-8 (5R,6R)-5-((dimethyl(phenyl)silyl)methyl)-6-(furan-2-yl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-77-9 (5R,6R)-5-((dimethyl(phenyl)silyl)methyl)-6-(fthiophen-2-yl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-74-6 (5R,6R)-6-(3,5-bis(trifluoromethyl)phenyl)-5-((dimethyl(phenyl)silyl)methyl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-71-3 (5R,6R)-6-(3,5-di-tert-butylphenyl)-5-((dimethyl(phenyl)silyl)methyl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-73-5 (5R,6R)-5-((dimethyl(phenyl)silyl)methyl)-6-(4-fluorophenyl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-72-4 (5R,6R)-5-((dimethyl(phenyl)silyl)methyl)-3-((S)-2-hydroxy-1-phenylethyl)-6-(4-methoxyphenyl)-5-methyl-1,3-oxazinane-2,4-dione 
• 1257664-75-7 4-((5R,6R)-5-((dimethyl(phenyl)silyl)methyl)-3-((S)-2-hydroxy-1-phenylethyl)-5-methyl-2,4-dioxo-1,3-oxazinan-6-yl)benzonitrile 
• 154499-37-3 (4S)-3-<(2R)-methyl-5-hexenoyl>-4-phenyl-2-oxazolidinone 

Relevant articles and documents

Copper-catalysed domino silylative aldol reaction leading to stereocontrolled chiral quaternary carbons

(Chemical Equation Presented) Asymmetric aldol reaction: A domino silylation-aldol reaction between enoyloxazolidinones and various aldehydes has been developed (see scheme). The process catalysed by a copper complex in the presence of a borosilane led to high diastereoselectivities. Yields between 59 and 90 % and d.r. values between 78:22 to 95:5 were obtained. When methacryloyloxazolidinones were used, a controlled chiral quaternary carbon was generated. BPin=4,4,5,5-tetramethyl-1,3,2dioxaborolan-2-yl.

AN EFFICIENT SYNTHESIS OF (2R,5R)- AND (2R,5S)-2-METHYL-5-HYDROXYHEXANOIC ACID LACTONES

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