15456-86-7Relevant articles and documents
Methods for treating neisseria gonorrhoeae infection with substituted 1,2-dihydro-2A,5,8A-triazaacenaphthylene-3,8-diones
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Page/Page column 137, (2020/07/21)
The present invention relates to methods for treating Neisseria Gonorrhoeae infection which comprises administering to a subject in need thereof novel 1,2-dihydro-2a,5,8a-triazaacenaphthylene-3,8-dione compounds: or pharmaceutically acceptable salts thereof and/or corresponding pharmaceutical compositions.
A general approach to access 5,6-dihydroindolo-naphthyridine ring system
He, Shuwen,Li, Peng,Dai, Xing,Liu, Hong,Lai, Zhong,Xiao, Dong,McComas, Casey C.,Du, Chunyan,Liu, Yuehui,Yin, Jingjun,Dang, Qun,Zorn, Nicolas,Peng, Xuanjia,Nargund, Ravi P.,Palani, Anandan
supporting information, p. 1373 - 1375 (2017/03/17)
We report a general approach for the synthesis of 5,6-dihydroindolo-naphthyridine ring system via an intramolecular cyclization of the indole NH to an alkene moiety as the key step.
Access to 4-alkylaminopyridazine derivatives via nitrogen-assisted regioselective pd-catalyzed reactions
Blaise, Emilie,Kümmerle, Arthur E.,Hammoud, Hassan,De Arajo-Jnior, Jo Xavier,Bihel, Frdric,Bourguignon, Jean-Jacques,Schmitt, Martine
, p. 10311 - 10322 (2015/02/19)
3-Substituted, 6-substituted, and unsymmetrical 3,6-disubstituted 4-alkylaminopyridazines were prepared from a sequence of three chemo- and regioselective reactions combining amination and palladium-catalyzed cross-coupling reactions, such as reductive dehalogenation and Suzuki-Miyaura reactions. Extension of the methodology to Sonogashira reaction yielded a novel class of 3-substituted pyrrolopyridazines.