154627-62-0Relevant articles and documents
Tandem oxidative radical fragmentation-rearrangement of 2-amino-1,3-benzylidene acetals: A short entry to densely functionalised fully differentiated oxazolidinones
Mcnulty, James,Calzavara, Janice
, p. 6771 - 6774 (2013/06/04)
The discovery of a novel tandem fragmentation-rearrangement process from N-Boc-protected benzylidene acetals is reported. The reaction proceeds via free-radical initiation and terminates through a 5-exo-tet ionic fragmentation process leading to biologically useful, densely functionalised oxazolidinones.
A convergent synthesis of the immunosuppressant FTY720 employing aqueous Wittig chemistry
Calzavara, Janice,McNulty, James
supporting information; experimental part, p. 5672 - 5675 (2011/11/06)
A short, convergent synthesis of the immunosuppressant FTY720 is described involving the use of 4-hydroxymethylbenzaldehyde as a pivotal intermediate. A double Wittig strategy was developed to connect this dual-functional aldehyde with an alkyl-tether and to a readily available TRIS-derivative leading to an efficient synthesis of the target molecule.
The total synthesis of antrimycin D(v)
Schmidt,Riedl
, p. 1186 - 1187 (2007/10/02)
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