154748-49-9 Usage
Description
Carbamic acid, (3-oxocyclobutyl)-, 1,1-dimethylethyl ester (9CI) is an organic compound with the chemical structure of a carbamic acid ester. It is characterized by a cyclobutyl ring with a carbonyl group and an ester functional group attached to a 1,1-dimethylethyl moiety. Carbamic acid, (3-oxocyclobutyl)-, 1,1-dimethylethyl ester (9CI) is known for its potential applications in the pharmaceutical and chemical industries due to its unique structural features and reactivity.
Uses
Used in Pharmaceutical Industry:
Carbamic acid, (3-oxocyclobutyl)-, 1,1-dimethylethyl ester (9CI) is used as a synthetic intermediate for the preparation of 5-HT1-like receptor agonists. These agonists are important in the development of medications targeting various central nervous system disorders, such as migraine, anxiety, and depression.
Used in Antiviral Drug Synthesis:
In the field of antiviral drug development, Carbamic acid, (3-oxocyclobutyl)-, 1,1-dimethylethyl ester (9CI) is utilized to synthesize (oxadiazolyl)quinoline derivatives. These derivatives have been identified as highly potent inhibitors of the Hepatitis C Virus (HCV) NS4B protein, which plays a crucial role in the viral replication process. By targeting this protein, these inhibitors can potentially help in the development of effective treatments for HCV infections.
Used in Chemical Synthesis:
Carbamic acid, (3-oxocyclobutyl)-, 1,1-dimethylethyl ester (9CI) can also be employed as a versatile building block in the synthesis of various organic compounds. Its unique structural features and reactivity make it a valuable component in the development of new molecules with potential applications in various industries, such as agrochemicals, materials science, and specialty chemicals.
Form
Solid
Check Digit Verification of cas no
The CAS Registry Mumber 154748-49-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,7,4 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 154748-49:
(8*1)+(7*5)+(6*4)+(5*7)+(4*4)+(3*8)+(2*4)+(1*9)=159
159 % 10 = 9
So 154748-49-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H15NO3/c1-9(2,3)13-8(12)10-6-4-7(11)5-6/h6H,4-5H2,1-3H3,(H,10,12)
154748-49-9Relevant articles and documents
Preparation method of tert-butyl 3-oxocyclobutyl carbamate
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Paragraph 0046-0047, (2020/11/12)
The invention belongs to the technical field of medicines, and particularly relates to a preparation method of tert-butyl 3-oxocyclobutyl carbamate (I). The method comprises the following steps: protecting a compound IV to generate a compound III, carrying out Hofmann degradation reaction to obtain a compound II, and finally, carrying out deprotection to obtain a compound I. Compared with the prior art, the method is low in technical route cost and mild in reaction condition, avoids the use of toxic reagents with larger danger coefficients, is green and environment-friendly, and has good application value.
Novel CDK inhibitory compounds, preparation method thereof, pharmaceutical composition for use in preventing or treating CDK relating diseases containing the same as an active ingredient
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Paragraph 0287-0290, (2018/10/24)
The present invention relates to a novel CDK inhibitory compound, a method for manufacturing the same, and a pharmaceutical composition for preventing or treating a CDK-related disease containing the compound as an active ingredient. The novel CDK inhibit
METHODS OF TREATING PULMONARY DISEASES AND DISORDERS
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Paragraph 0117; 0250, (2017/07/14)
The present disclosure features disclosed method of treating disorders such as COPD, bronchitis and/or asthma using disclosed compounds, optionally together with one or more additional active agents. Contemplated methods include administrating orally or by inhalation to a patient one or more disclosed compounds.
