15476-33-2

Basic information

• Product Name: 1,2,3-Propanetriol,1-(2-phenyl-2H-1,2,3-triazol-4-yl)-, (1R,2R)-
• Synonyms: 1,2,3-Propanetriol,1-(2-phenyl-2H-1,2,3-triazol-4-yl)-, D-threo- (8CI); 1,2,3-Propanetriol, 1-(2-phenyl-2H-1,2,3-triazol-4-yl)-,[R-(R*,R*)]-; 2H-1,2,3-Triazole, 1,2,3-propanetriol deriv.; D-Xylose,phenylosotriazole
• CAS NO: 15476-33-2
• Molecular Formula: C11H13 N3 O3
• Molecular Weight: 235.243
• Mol File: 15476-33-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,2,3-Propanetriol,1-(2-phenyl-2H-1,2,3-triazol-4-yl)-, (1R,2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Propanetriol,1-(2-phenyl-2H-1,2,3-triazol-4-yl)-, (1R,2R)-(15476-33-2)
• EPA Substance Registry System: 1,2,3-Propanetriol,1-(2-phenyl-2H-1,2,3-triazol-4-yl)-, (1R,2R)-(15476-33-2)

Safety Data

• Hazardous Substances Data: 15476-33-2(Hazardous Substances Data)

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 9 carbon (C), 13 hydrogen (H), 3 nitrogen (N), and 3 oxygen (O) atoms.
2. Derivative of 1,2,3-propanetriol (Glycerol)

Explanation

The compound is derived from 1,2,3-propanetriol, which is a simple polyol compound commonly known as glycerol. It has three hydroxyl (-OH) groups attached to a three-carbon chain.
3. Phenyltriazole group attachment

Explanation

The compound has a phenyltriazole group attached to it, which is a combination of a phenyl ring (a six-carbon aromatic ring with a hydrogen atom attached to each carbon) and a triazole ring (a five-membered ring with three nitrogen atoms and two carbon atoms).

Explanation

The compound exists in two stereoisomeric forms, which are mirror images of each other. The (1R,2R)designation indicates the specific configuration of the hydroxyl groups on the glycerol molecule, with the R (rectus) configuration at both the first and second carbon atoms.

Explanation

Due to its unique structural features and potential biological activities, the compound may have applications in various fields, such as the development of new drugs, agrochemicals for agriculture, or novel materials for various industries.
6. Further research needed

Explanation

To fully understand the properties and potential uses of this chemical compound, additional research is required. This may include studying its chemical reactivity, stability, and interactions with other molecules, as well as evaluating its safety and efficacy in specific applications.

Stereoisomeric forms

(1R,2R)-

Potential applications

Pharmaceuticals, agrochemicals, material sciences

Upstream product

• 6631-53-4 2-phenyl-4-(D-erithro-1',2',3'-trihydroxypropyl)-2H-1,2,3-triazole 
• 15476-35-4 (1R,2S)-1-(2-phenyl-2H-[1,2,3]triazol-4-yl)-propane-1,2,3-triol 
• 3322-01-8 D-erythropentose phenylosazone 
• 534-97-4 glucosazone 
• 50-99-7 D-glucose 
• 25581-23-1 2-phenyl-4-(D-arabino-di-O-1',2',3',4'-isopropylidenebutyl)-2H-1,2,3-triazole 
• 100-63-0 phenylhydrazine 
• 426260-72-2 2-phenyl-4-(D-threo-O-1',2'-isopropylidene-3'-hydroxypropyl)-2H-1,2,3-triazole 
• 5934-40-7 D-threo-[2]pentosulose-bis-phenylhydrazone 
• 6341-06-6 2-phenyl-4-(D-arabino-1',2',3',4'-tetrahydroxybutyl)-2H-1,2,3-triazole 
• 426260-71-1 2-phenyl-4-(D-arabino-O-1',2'-isopropylidene-3',4'-dihydroxybutyl)-2H-1,2,3-triazole 

Relevant articles and documents

Highly efficient and selective biocatalytic acylation studies on triazolylsugars

Different acid anhydrides (of C2 to C7 aliphatic fatty acids and benzoic acid) have been used to study the selective acylation of primary/secondary hydroxyl groups in 2-phenyl-4-(D-threo-1′,2′, 3′-trihydroxypropyl)-2H-1,2,3-triazole, 2-phenyl-4-(D-erythro-1′, 2′,3′-trihydroxypropyl)-2H-1,2,3-triazole, 2-phenyl-4-(D-arabino- 1′,2′,3′,4′-tetrahydroxybutyl)-2H-1,2,3-triazole and 2-phenyl-4-(D-lyxo-1′,2′,3′,4′-tetrahydroxybutyl)-2H-1, 2,3-triazole in the presence of Candida antarctica lipase B in diisopropyl ether. Among the different acid anhydrides, butanoic anhydride was found to be the most efficient acylating agent (for butanoylation); for acetylation, vinyl acetate gave the best results. The reactions with both these acylating agents were highly selective and efficient yielding exclusively the monoacylated products in 95-99% yields in 1-5 h.