155628-88-9

Basic information

• Product Name: 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol
• Synonyms: 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol
• CAS NO: 155628-88-9
• Molecular Weight: 194.23
• Mol File: 155628-88-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol(155628-88-9)
• EPA Substance Registry System: 1-(2',5'-dimethoxyphenyl)prop-2-en-1-ol(155628-88-9)

Safety Data

• Hazardous Substances Data: 155628-88-9(Hazardous Substances Data)

Upstream product

• 1826-67-1 vinyl magnesium bromide 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 3536-96-7 vinylmagnesium chloride 

Downstream Products

• 934170-62-4 2-[1-(1-cyclobutenyl)carboxyl-2-propenyl]-1,4-dimethoxybenzene 
• 79238-14-5 2,5-dimethoxyphenyl vinyl ketone 
• 89556-60-5 2',5'-dimethoxy-2-methylpropiophenone 
• 1430109-83-3 (E)-1,4-bis(2,5-dimethoxyphenyl)but-2-ene-1,4-dione 
• 1348155-56-5 1-(2',5'-dimethoxyphenyl)allyl acetate 
• 1433498-29-3 (2'S,3'S)-2-(2'',5''-dimethoxyphenyl)-5'-oxotetrahydrofuran-3'-yl (2S)-2-(acetyloxy)(phenyl)acetate 
• 1433498-28-2 (4S,5S)-4-hydroxy-5-(2',5'-dimethoxyphenyl)-4,5-dihydrofuran-2(3H)-one 
• 137744-78-6 methyl (E)-4-(2',5'-dimethoxyphenyl)but-3-enoate 

Relevant articles and documents

Palladium-Catalyzed Synthesis of α-Methyl Ketones from Allylic Alcohols and Methanol

One-pot synthesis of α-methyl ketones starting from 1,3-diaryl propenols or 1-aryl propenols and methanol as a C1 source is demonstrated. This one-pot isomerization-methylation is catalyzed by commercially available Pd(OAc)2 with H2O as the only by-product. Mechanistic studies and deuterium labelling experiments indicate the involvement of isomerization of allyl alcohol followed by methylation through a hydrogen-borrowing pathway in these isomerization-methylation reactions.

Synthesis of the AB-ring pyranolactone substructure of granaticin A

A synthesis of the AB-ring substructure of granaticin A was developed. The pyranolactone moiety was stereoselectively accessed by Sharpless asymmetric dihydroxylation and subsequent oxa-Pictet-Spengler cyclization. The use of BF3·OEt2 resulted in the formation of the cis pyranolactone, whereas the combination of BF3·OEt2 with trifluoroacetic acid led to the trans isomer. The resulting hydroquinones were cleaved selectively by ozonolysis to dicarboxylic acids. An aryl Grignard reagent could be regioselectively added to unsymmetrical anhydrides. As an alternative strategy for the construction of the B-ring, a benzyne-furan cycloaddition could be established. Synthesis of the AB-ring substructure of granaticin A was accomplished. The pyranolactone moiety was stereoselectively accessed by Sharpless asymmetric dihydroxylation and oxa-Pictet-Spengler cyclization. Ozonolysis of a hydroquinone led to pyranolactone anhydrides. Regioselective addition of a Grignard reagent to an unsymmetrical anhydride was observed. An alternative strategy was also investigated. Copyright

2-(3-oxoalk(en)yl)-3-isothiazolones and derivatives as antimicrobial agents

Antimicrobial compounds of the formula STR1 wherein R is hydrogen, halogen or (C1 -C4)alkyl group; R1 is hydrogen or halogen; alternatively, R and R1 may be taken together with the carbons to which they are attached to for