156130-68-6

Basic information

• Product Name: BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT
• Synonyms: BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID-DCHA;BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT;BOC-D-NVA(5-PHENYL)-OH DCHA;(alphaR)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]benzenepentanoic acid;(R)-5-Phenyl-2-(tert-butoxycarbonylamino)pentanoic acid;(R)-alpha-[[(1,1-Dimethylethoxy)carbonyl]amino]benzenepentanoic acid;(R)-N-tert-Butoxylcarbonyl-2-amino-5-phenylpentanoic acid;Boc-D-2-AMino-5-phenyl-pentanoic acid
• CAS NO: 156130-68-6
• Molecular Formula: C₁₆H₂₃NO₄
• Molecular Weight: 474.68
• Product Categories: Phenylalanine analogs and other aromatic alpha amino acids;Amino Acid Derivatives;a-amino
• Mol File: 156130-68-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.121
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT(156130-68-6)
• EPA Substance Registry System: BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT(156130-68-6)

Safety Data

• Hazardous Substances Data: 156130-68-6(Hazardous Substances Data)

Usage

General Description

BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT is a chemical compound that consists of BOC-D-2-amino-5-phenyl-pentanoic acid combined with DCHA salt. BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT is commonly used in chemical and pharmaceutical research as a building block for the synthesis of peptides and other organic molecules. BOC-D-2-AMINO-5-PHENYL-PENTANOIC ACID DCHA SALT plays a crucial role in the development of new drugs and materials due to its ability to react with various functional groups and form complex chemical structures. Its properties and reactivity make it a valuable tool in the field of organic chemistry and drug discovery.

Upstream product

• 206360-08-9 2-tert-butoxycarbonylamino-5-phenyl-pentanoic acid ethyl ester 
• 637-59-2 1-Bromo-3-phenylpropane 
• 108019-30-3 DL-N-acetyl-2-amino-5-phenylpentanoic acid 
• 52161-73-6 2-acetylamino-2-(3-phenyl-propyl)malonic acid diethyl ester 
• 62777-26-8 D-N-acetyl-2-amino-5-phenylpentanoic acid 
• 1400695-38-6 tert-butyl ((2R,3R)-1,2-dihydroxy-6-phenylhexan-3-yl)carbamate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 185148-25-8 [4-phenyl-1-(3-phenyl-8-aza-bicyclo[3.2.1]octane-8-carbonyl)-butyl]-carbamic acid tert-butyl ester 
• 185148-29-2 [4-phenyl-1-(3-o-tolyl-8-aza-bicyclo[3.2.1]octane-8-carbonyl)-butyl]-carbamic acid tert-butyl ester 
• 593266-77-4 2-[8-(2-tert-butoxycarbonylamino-5-phenyl-pentanoyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-benzoic acid ethyl ester 
• 185099-74-5 2-[(1R,3S,5S)-8-((R)-2-tert-Butoxycarbonylamino-5-phenyl-pentanoyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-benzoic acid ethyl ester 
• 185148-35-0 2-[(1R,3R,5S)-8-((R)-2-tert-Butoxycarbonylamino-5-phenyl-pentanoyl)-8-aza-bicyclo[3.2.1]oct-3-yl]-benzoic acid ethyl ester 
• 943984-32-5 C₃₇H₄₄N₂O₅ 
• 943984-31-4 C₃₇H₄₄N₂O₅ 
• 416856-10-5 [1-(1-{[5-(4-chloro-phenyl)-3,3-dimethyl-1,1-dioxo-2,3-dihydro-1H-1λ⁶-isothiazol-4-ylmethyl]-ethyl-carbamoyl}-4-phenyl-butylcarbamoyl)-1-methyl-ethyl]-carbamic acid tert-butyl ester 

Relevant articles and documents

Asymmetric synthesis of allylic amines: Via hydroamination of allenes with benzophenone imine

Rhodium-catalyzed highly regio- and enantioselective hydroamination of allenes is reported. Exclusive branched selectivities and excellent enantioselectivities were achieved applying a rhodium(i)/Josiphos catalyst. This method permits the practical synthesis of valuable α-chiral allylic amines using benzophenone imine as ammonia carrier.

Structure activity studies of the serine-AIB dipeptide domain in 2,3-dihydroisothiazole based growth hormone secretagogues

A series of growth hormone secretagogues (GHSs) based on 2,3-dihydroisothiazole has been synthesized in the search for a potential treatment of growth hormone deficiency or frailty in the elderly. This paper describes the evaluation of the SAR of the benzyl-d-Ser-aminoisobutyric acid dipeptide fragment. Introduction of substituents in the peptide backbone and in the phenyl ring has been investigated, as well as replacements for the benzyl group and for the AIB residue. A number of modifications resulted in enhanced potency over the parent benzyl-d-Ser-AIB derivative.

Spiro piperidines and homologs promote release of growth hormone

There are disclosed certain novel compounds identified as spiro piperidines and homologs which promote the release of growth hormone in humans and animals. This property can be utilized to promote the growth of food animals to render the production of edible meat products more efficient, and in humans, to treat physiological or medical conditions characterized by a deficiency in growth hormone secretion, such as short stature in growth hormone deficient children, and to treat medical conditions which are improved by the anabolic effects of growth hormone. Growth hormone releasing compositions containing such spiro compounds as the active ingredient thereof are also disclosed.