156557-88-9

Basic information

• Product Name: (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid
• Synonyms: (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid
• CAS NO: 156557-88-9
• Molecular Weight: 289.331
• Mol File: 156557-88-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid(156557-88-9)
• EPA Substance Registry System: (1R,3R,5R)-2-(benzyloxycarbonyl)-2-azabicyclo<3.3.0>octane-3-carboxylic acid(156557-88-9)

Safety Data

• Hazardous Substances Data: 156557-88-9(Hazardous Substances Data)

Upstream product

• 129101-19-5 (all-R)-2-Azabicyclo[3.3.0]octan-3-oic acid benzyl ester p-toluenesulfonate 
• 138877-09-5 (1R,3R,5R)-benzyl 2-azabicyclo<3.3.0>octane-3-carboxylate hydrochloride 
• 135214-81-2 (1R,3R,5R)-2-azabicyclo<3.3.0>octane-3-carboxylic acid hydrochloride 
• 501-53-1 benzyl chloroformate 
• 128900-19-6 (1R,3R,5R)-2-azabicyclo<3.3.0>octane-3-carboxylic acid 

Downstream Products

• 156481-90-2 (all-R)-2-(Benzyloxycarbonyl)-2-azabicyclo<3.3.0>octan-3-carbonsaeure-pyrrolidid 
• 156481-92-4 (2S,1'R,3'R,5'R)-2'-(Benzyloxycarbonyl)-2'-azabicyclo<3.3.0>octan-3'-carbonsaeure-2-(methoxymethyl)pyrrolidid 
• 156481-94-6 (all-R)-2-(Benzyloxycarbonyl)-2-azabicyclo<3.3.0>octan-3-carboxamid 
• 156481-95-7 (all-R)-2-Azabicyclo<3.3.0>octan-3-carboxamid 
• 183021-38-7 (2R,3aR,6aR)-2-((3aR,6aR)-Hexahydro-cyclopenta[b]pyrrole-1-carbonyl)-hexahydro-cyclopenta[b]pyrrole-1-carboxylic acid benzyl ester 
• 185420-82-0 (2R,3aR,6aR)-Octahydro-cyclopenta[b]pyrrole-2-carboxylic acid dimethylamide 

Relevant articles and documents

HYDROXAMATE-BASED INHIBITORS OF DEACETYLASES

The present teachings relate to compounds of Formula (I): and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, wherein R1, R2, R3, R4, R5, ring A, and Z are as defined herein

Chemical differentiation of enantiotopic groups: Diastereoselective opening of a prochiral dilactone

Prochiral dilactone 1 has been synthesized and subjected to diastereoselective nucleophilic opening. The structural features of chiral, enantiomerically pure nucleophiles have been optimized regarding their capability to perform prochiral recognition at dilactone 1. 3-Ketoglutaric mono acid products 2 of dilactone opening, which are versatile building blocks for natural product synthesis, have been obtained in diastereomeric ratios up to 84:16 and were enriched by subsequent crystallization to 97.5:2.5.