15658-35-2 Usage
Description
6,6'-Dithiodinicotinic acid is a sulphydryl reagent that is known to react with thiols, resulting in the formation of a disulfide and 6-mercaptonicotinic acid. It is characterized by its tan powder appearance and has been reported to interact with the homogenates of Ehrlich ascites cells.
Uses
Used in Biochemical Research:
6,6'-DITHIODINICOTINIC ACID is used as a specific thiol blocker for investigating the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of Ehrlich ascites tumor cells.
Used in Enzyme Studies:
6,6'-DITHIODINICOTINIC ACID is used as a modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase.
Used in Plant Physiology:
6,6'-DITHIODINICOTINIC ACID is used as a dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin-stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes.
Used in Chemical Synthesis:
6,6'-DITHIODINICOTINIC ACID is used as a water-soluble reagent in a study for introducing a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group in buffered saline.
Used in Analytical Chemistry:
6,6'-DITHIODINICOTINIC ACID is used as a chromogen for sulfhydryl groups in the Ellman method for cholinesterase determination.
Used in Clinical Chemistry:
6,6'-DITHIODINICOTINIC ACID is used for the spectrophotometric determination of thiols and total glutathione in human blood.
Check Digit Verification of cas no
The CAS Registry Mumber 15658-35-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,6,5 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 15658-35:
(7*1)+(6*5)+(5*6)+(4*5)+(3*8)+(2*3)+(1*5)=122
122 % 10 = 2
So 15658-35-2 is a valid CAS Registry Number.