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156699-39-7

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156699-39-7 Usage

General Description

"(3S)-N,N'-bis-(t-butoxycarbonyl)hexahydropyridazine-3-carboxylic acid" is a chemical compound that is commonly used in the pharmaceutical industry. It belongs to the class of pyridazine derivatives. (3S)-N,N'-bis-(t-butoxycarbonyl)hexahydropyridazine-3-carboxylic acid is an important intermediate in the synthesis of various pharmaceutical drugs and is known for its biological activity. The t-butoxycarbonyl groups in the compound serve as protective groups that can be removed under mild conditions to uncover the active functional groups. (3S)-N,N'-bis-(t-butoxycarbonyl)hexahydropyridazine-3-carboxylic acid plays a crucial role in the development of new drugs and medications, making it an important chemical in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 156699-39-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,6,9 and 9 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156699-39:
(8*1)+(7*5)+(6*6)+(5*6)+(4*9)+(3*9)+(2*3)+(1*9)=187
187 % 10 = 7
So 156699-39-7 is a valid CAS Registry Number.

156699-39-7Downstream Products

156699-39-7Relevant articles and documents

Total synthesis and structure elucidation of JBIR-39: A linear hexapeptide possessing piperazic acid and γ-hydroxypiperazic acid residues

Yoshida, Masahito,Sekioka, Naoki,Izumikawa, Miho,Kozone, Ikuko,Takagi, Motoki,Shin-ya, Kazuo,Doi, Takayuki

supporting information, p. 3031 - 3041 (2015/02/05)

The total synthesis and stereochemical structural elucidation of JBIR-39, containing four nonproteinogenic piperazic acid (Piz) residues, is reported. The synthesis includes Sc(OTf)3-catalyzed acylation of a Piz(γ-OTBS) derivative with piperazi

Synthesis of the tripeptide domain of sanglifehrins using asymmetric phase-transfer catalysis

White, James D.,Suttisintong, Khomson

, p. 2757 - 2762 (2013/04/23)

The tripeptide (S)-valinyl-(S)-m-hydroxyphenylalanyl-(3S)-piperazate common to immunosuppressant sanglifehrins was synthesized from the constituent amino acid residues in nine steps and 42% overall yield. A key construction was the installation of (S) absolute configuration in m-hydroxyphenylalanine using asymmetric phase-transfer catalysis in the presence of N-(1-naphthyl) cinchonidinium bromide. Cbz-protected (S)-valine was first coupled to the amino group of (S)-m-triisopropylsilyloxyphenylalanine tert-butyl ester, and the resulting dipeptide after ester cleavage was linked to (3S)-methyl piperazate.

Stereochemical Definition and Chirospecific Synthesis of the Peptide Deformylase Inhibitor Sch 382583

Coats, Reed A.,Lee, Sheng-Lian,Davis, Kari A.,Patel, Kanu M.,Rhoads, Elaine K.,Howard, Michael H.

, p. 1734 - 1737 (2007/10/03)

The recently reported natural product Sch 382583 (1), an inhibitor of peptide deformylase, has been synthesized in 16 steps from commercially available starting materials. The three chiral centers were set by a combination of chiral auxiliary and chiral p

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