156699-53-5

Basic information

• Product Name: 1,1'-(1-benzyl-2,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrrole-2,4-diyl)diethanone
• Synonyms: 1,1'-(1-benzyl-2,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrrole-2,4-diyl)diethanone
• CAS NO: 156699-53-5
• Molecular Weight: 285.343
• Mol File: 156699-53-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,1'-(1-benzyl-2,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrrole-2,4-diyl)diethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-(1-benzyl-2,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrrole-2,4-diyl)diethanone(156699-53-5)
• EPA Substance Registry System: 1,1'-(1-benzyl-2,5-dimethyl-3-oxo-2,3-dihydro-1H-pyrrole-2,4-diyl)diethanone(156699-53-5)

Safety Data

• Hazardous Substances Data: 156699-53-5(Hazardous Substances Data)

Upstream product

• 23652-86-0 (Z)-4-(benzylamino)-3-penten-2-one 
• 21396-42-9 4-benzylaminopent-3-en-2-one 
• 123-54-6 acetylacetone 
• 100-46-9 benzylamine 
• 27871-55-2 3,4-diacetylhex-3-ene-2,5-dione 

Downstream Products

• 1002555-92-1 2-acetyl-1-benzyl-2,5-dimethyl-1,2-dihydropyrrol-3-one 

Relevant articles and documents

H2O2-promoted reactions of aliphatic primary amines with 1,3-diketones for the synthesis of 1 H -pyrrol-3(2 H)-ones at ambient temperature in water

A green organic reaction of aliphatic primary amines with 1,3-diketones promoted by 30% aqueous H2O2 has been developed. It provides an inexpensive, regioselective, and efficient approach to 1H-pyrrol-3(2H)-ones with high yields from the simple and readily available starting materials in one pot via multicomponent tandem cyclization reactions and C-C cleavage under very mild and environmentally friendly reaction conditions.

Efficient synthesis of highly substituted pyrrolin-4-ones via PIFA-mediated cyclization reactions of enaminones

A convenient and efficient synthesis of highly substituted pyrrolin-4-ones is developed via the PIFA-mediated cyclization reactions of readily available enaminones, and a mechanism involving sequential cleavage of N - C bond, formation of new N - C bond, intramolecular addition reaction, and benzilic acid type rearrangement is proposed.