15679-19-3 Usage
Description
2-Ethoxythiazole is a colorless to light yellow liquid with a strong, burnt, nutty, and roasted meat-like odor. It is characterized by its musty, vegetative, brothy, nutty, and coffee-like taste with a slight rubbery nuance at a concentration of 2.0 ppm.
Uses
Used in Flavor and Fragrance Industry:
2-Ethoxythiazole is used as a flavoring agent for its musty, vegetative, green, phenolic, nutty, coffee, and brothy aroma characteristics at 2.0%. It is particularly useful in creating complex and rich flavor profiles in the food and beverage industry.
Used in Perfumery:
2-Ethoxythiazole is used as a fragrance ingredient for its unique and strong burnt, nutty, and roasted meat-like odor. It can be employed in the creation of various perfumes and colognes to add depth and complexity to the scent.
Used in Aromatherapy:
Due to its distinct and strong aroma, 2-Ethoxythiazole can be used in aromatherapy applications to provide a unique sensory experience and potentially evoke specific moods or emotions.
Preparation
2-Bromothiazole is treated with sodium alkoxides to give 2-alkoxythiaxole
Check Digit Verification of cas no
The CAS Registry Mumber 15679-19-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,6,7 and 9 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15679-19:
(7*1)+(6*5)+(5*6)+(4*7)+(3*9)+(2*1)+(1*9)=133
133 % 10 = 3
So 15679-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H7NOS/c1-2-7-5-6-3-4-8-5/h3-4H,2H2,1H3
15679-19-3Relevant articles and documents
Cs2CO3-Promoted C?O Coupling Protocol Enables Solventless (Hetero)aryl Ether Synthesis under Air Atmosphere
Jiang, Bowen,Chen, Cheng,Fan, Guang-Gao,Sang, Wei,Cheng, Hua,Zhang, Rui,Yuan, Ye,Li, Qi-Zhong,Verpoort, Francis
supporting information, (2022/02/05)
In this work, a Cs2CO3-promoted synthetic approach was identified for (hetero)aryl ether synthesis via the C?O coupling of various (hetero)aryl chlorides and alcohols/phenol. To our delight, the reactions could be carried out under transition-metal-free and solvent-free conditions. Moreover, analytical-grade reagents and air atmosphere were readily tolerated. To showcase the practical usefulness of the present protocol, the assembly of a bioactive molecule was facilely realized and the gram-scale production of selected ether products was also efficiently accomplished. In addition, density functional theory (DFT) studies, along with a few mechanistic experiments, were conducted to elucidate a proposed reaction pathway and rationalize the pivotal role of Cs2CO3 in promoting this process. Hopefully, this work could provide useful information for researchers who are engaging in C?O cross-coupling reactions.