157798-12-4 Usage
Description
5-NONYLOXYTRYPTAMINE OXALATE is a chemical compound that functions as a selective agonist for the 5-HT1B Serotonin receptor and mimics the properties of polysialic acid, modulating neuronal and glial functions in cell culture.
Uses
Used in Pharmaceutical Industry:
5-NONYLOXYTRYPTAMINE OXALATE is used as a pharmaceutical agent for its agonistic effects on the 5-HT1B Serotonin receptor. This property makes it potentially useful in the development of treatments for various conditions related to serotonin receptor dysregulation.
Used in Neuroscientific Research:
5-NONYLOXYTRYPTAMINE OXALATE is used as a research tool for studying the role of the 5-HT1B Serotonin receptor in neuronal and glial functions. Its ability to mimic polysialic acid allows researchers to investigate the underlying mechanisms of various neurological processes and disorders.
Used in Drug Development:
5-NONYLOXYTRYPTAMINE OXALATE is used as a lead compound in the development of new drugs targeting the 5-HT1B Serotonin receptor. Its selective agonistic activity can be leveraged to create more effective and targeted treatments for conditions such as migraine, anxiety, and depression.
Check Digit Verification of cas no
The CAS Registry Mumber 157798-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,7,9 and 8 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 157798-12:
(8*1)+(7*5)+(6*7)+(5*7)+(4*9)+(3*8)+(2*1)+(1*2)=184
184 % 10 = 4
So 157798-12-4 is a valid CAS Registry Number.
InChI:InChI=1/C19H30N2O.C2H2O4/c1-2-3-4-5-6-7-8-13-22-17-9-10-19-18(14-17)16(11-12-20)15-21-19;3-1(4)2(5)6/h9-10,14-15,21H,2-8,11-13,20H2,1H3;(H,3,4)(H,5,6)
157798-12-4Relevant articles and documents
Tryptamine analogs with 5-HT1D selectivity
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, (2008/06/13)
Described herein are tryptamine analogs that display high binding affinity and selectivity for the 5-HT1Dβ receptor, of the formula: STR1 wherein R 1 represents a chain selected from C 8-11 alkyl, C 7-10 alkoxy, C 8-11 alkanoyl and C 7-10 alkanoyloxy wherein said chain is optionally substituted by hydroxyl, C 1-4 alkyl or C 1-4 alkoxy and wherein one of the intervening carbons of said chain is optionally replaced with a heteroatom selected from oxygen, nitrogen and sulfur;R 2 and R 3 each independently represent H or C 1-3 alkyl; andR 4 represents H, C 1-4 alkyl, aryl or arylC 1-4 alkyl;The compounds are useful as reagents for receptor identification and in receptor-based drug screening programs, and can also be used therapeutically to treat conditions for which administration of a 5-HT1D ligand is indicated, for example in the treatment of migraine.
