157810-81-6 Usage
Description
Indinavir sulfate is a potent HIV-1 protease inhibitor belonging to the hydroxyaminopentane amide class. It selectively inhibits the HIV-1 protease, thus preventing the formation of mature viral particles and their subsequent release from infected cells. This action helps in controlling the viral load and progression of HIV infection. Indinavir sulfate is a crystalline solid and has been found to be effective against multiple HIV-1 variants in cell-based assays.
Uses
Used in Pharmaceutical Industry:
Indinavir sulfate is used as an antiviral agent for the treatment of HIV-1 infection. It works by inhibiting the HIV-1 protease, which is essential for the replication of the virus. By blocking this enzyme, Indinavir sulfate prevents the formation of mature, infectious viral particles, thereby reducing the viral load and slowing down the progression of the disease.
Used in COVID-19 Research:
Indinavir sulfate is also used as a COVID-19-related research product. It has been investigated for its potential to inhibit the main protease (Mpro) of the SARS-CoV-2 virus, which is responsible for the replication and maturation of the virus. By inhibiting this enzyme, Indinavir sulfate may help in controlling the replication of the virus and could potentially be used in the development of treatments for COVID-19.
Hazard
Moderately toxic by ingestion.
Check Digit Verification of cas no
The CAS Registry Mumber 157810-81-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,8,1 and 0 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 157810-81:
(8*1)+(7*5)+(6*7)+(5*8)+(4*1)+(3*0)+(2*8)+(1*1)=146
146 % 10 = 6
So 157810-81-6 is a valid CAS Registry Number.
