157831-24-8

Basic information

• Product Name: ((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-(4-methoxy-benzyl)-amine
• Synonyms: ((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-(4-methoxy-benzyl)-amine
• CAS NO: 157831-24-8
• Molecular Weight: 539.671
• Mol File: 157831-24-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: ((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-(4-methoxy-benzyl)-amine(CAS DataBase Reference)
• NIST Chemistry Reference: ((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-(4-methoxy-benzyl)-amine(157831-24-8)
• EPA Substance Registry System: ((3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yl)-(4-methoxy-benzyl)-amine(157831-24-8)

Safety Data

• Hazardous Substances Data: 157831-24-8(Hazardous Substances Data)

Upstream product

• 160549-10-0 2,3,5-tri-O-benzyl-D-arabinofuranose 
• 2393-23-9 4-methoxy-benzylamine 
• 60933-68-8 3,4,6-tri-O-benzyl-β-D-arabinofuranoside 

Downstream Products

• 603127-06-6 (2S,3R,4S)-3,4-Bis-benzyloxy-2-((S)-11-methoxymethoxy-13-methyl-tetradec-1-ynyl)-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 291509-99-4 [2,3-bis-benzyloxy-4-(tert-butyl-dimethyl-silanyloxy)-1-(3-hydroxy-propyl)-butyl]-carbamic acid tert-butyl ester 
• 291509-98-3 {1-[1,2-bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-propyl]-pent-4-enyl}-carbamic acid tert-butyl ester 
• 291510-00-4 2-[1,2-bis-benzyloxy-3-(tert-butyl-dimethyl-silanyloxy)-propyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 291509-96-1 (3S,4R,5S)-3,4-Bis-benzyloxy-5-but-3-enyl-1-(4-methoxy-benzyl)-pyrrolidin-2-one 
• 291509-97-2 (2S,3R,4S)-3,4-Bis-benzyloxy-2-but-3-enyl-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312515-19-8 (2S,3R,4R,5R)-3,4-Bis-benzyloxy-2-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-5-(1,2-dihydroxy-ethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312515-05-2 (2S,3R,4R,5R)-3,4-Bis-benzyloxy-2-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-5-methoxymethoxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312515-01-8 {(1S,2R,3R,4S)-2,3-Bis-benzyloxy-1-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-4-hydroxy-hex-5-enyl}-carbamic acid tert-butyl ester 
• 312515-21-2 (2S,3R,4R,5R)-3,4-Bis-benzyloxy-2-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-5-hydroxymethyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312515-03-0 (2S,3R,4R,5R)-3,4-Bis-benzyloxy-2-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-5-vinyl-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312514-99-1 (2S,3R,4S)-3,4-Bis-benzyloxy-2-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-5-oxo-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 312515-29-0 (3S,4R,5S)-3,4-Bis-benzyloxy-5-[(S)-3-(tert-butyl-diphenyl-silanyloxy)-1-methoxymethoxy-propyl]-pyrrolidin-2-one 

Relevant articles and documents

Asymmetric total synthesis of natural pyrrolizidine alkaloid, (+)-alexine

The total synthesis of the potent glycosidase inhibitor (+)-alexine with five contiguous stereogenic centres [(1R,2R,3R,7S,7aS)-3-hydroxymethyl-1,2,7-trihydroxypyrrolizidine alkaloid] is described featuring the efficient and stereodefined novel elaboratio

Stereocontrolled synthesis of a trihydroxylated pyrrolizidine alkaloid, 7-deoxyalexine

An enantiomerically and diastereomerically pure route has been developed for the asymmetric synthesis of (1R,2R,3R,7aS)-trihydroxylated pyrrolizidine alkaloid, 7-deoxyalexine, featuring the stereocontrolled elaboration of the functionalized homochiral lactam derived from 2,3,5-tri-O-obenzylol-β-D- arabinofuranose.