15789-02-3 Usage
Description
N-BENZYL-3-HYDROXY-BENZAMIDE, also known as N-(phenylmethyl)-3-hydroxybenzamide, is a chemical compound with the molecular formula C14H13NO2. It is a benzamide derivative featuring a benzyl group attached to the nitrogen atom and a hydroxy group on the benzene ring, providing both amide and alcohol functional groups. This unique structure and its properties make N-BENZYL-3-HYDROXY-BENZAMIDE a valuable tool in organic chemistry and drug discovery, often used as a building block in chemical synthesis and pharmaceutical research, as well as in the development of potential drug candidates.
Uses
Used in Chemical Synthesis:
N-BENZYL-3-HYDROXY-BENZAMIDE is used as a building block for the synthesis of various complex organic compounds. Its amide and alcohol functional groups allow for a wide range of chemical reactions, making it a versatile component in the creation of new molecules.
Used in Pharmaceutical Research:
In pharmaceutical research, N-BENZYL-3-HYDROXY-BENZAMIDE is utilized as a starting material for the development of potential drug candidates. Its unique structure can be modified to create new compounds with specific therapeutic properties, contributing to the advancement of medicine.
Used in Drug Development:
N-BENZYL-3-HYDROXY-BENZAMIDE plays a crucial role in drug development, where its structure can be optimized to enhance the efficacy and safety of new pharmaceuticals. Its presence in a compound can influence pharmacokinetics, pharmacodynamics, and drug-target interactions, making it an essential component in the design of novel therapeutic agents.
Used in Organic Chemistry Studies:
As a benzamide derivative with both amide and alcohol functional groups, N-BENZYL-3-HYDROXY-BENZAMIDE is an important subject of study in organic chemistry. Researchers use it to explore reaction mechanisms, investigate the properties of functional groups, and develop new synthetic methods, furthering the understanding of organic chemistry principles.
Check Digit Verification of cas no
The CAS Registry Mumber 15789-02-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,8 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 15789-02:
(7*1)+(6*5)+(5*7)+(4*8)+(3*9)+(2*0)+(1*2)=133
133 % 10 = 3
So 15789-02-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H13NO2/c16-13-8-4-7-12(9-13)14(17)15-10-11-5-2-1-3-6-11/h1-9,16H,10H2,(H,15,17)
15789-02-3Relevant articles and documents
ISOQUINOLINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
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Page/Page column 168; 170; 173, (2021/02/12)
The present invention relates to a compound suitable for use as a kinase inhibitor
Microwave-assisted N-debenzylation of amides with triflic acid
Rombouts, Frederik,Franken, Dennis,Martínez-Lamenca, Carolina,Braeken, Mirielle,Zavattaro, Chiara,Chen, Jinsheng,Trabanco, Andrés A.
experimental part, p. 4815 - 4818 (2010/10/02)
A new and facile microwave-assisted protocol for the debenzylation of N-benzylamides with triflic acid has been developed. Both secondary and tertiary aliphatic or aromatic amides are obtained in moderate to good yields.
Potential Central Nervous System Active Agents. 1. Synthesis of Aromatic N-Benzyl Amides
Agwada, Vincent C.
, p. 479 - 481 (2007/10/02)
The preparation and spectral properties (IR, MS, NMR) are given for 18 aromatic N-benzyl amides, variously substituted on the acyl part, including four new ones and an (E)-cinnamide derivative.The amides were prepared by heating the appropriate N-benzylammonium salt in o-xylene, or from the reaction of the corresponding acid chloride with benzylamine.The occurrence of an intense peak in their mass spectra, which corresponds to the loss of the N-acyl substituent without hydrogen transfer, is reported.
