15796-82-4

Basic information

• Product Name: 4,4'-DI-TERT-BUTYLBENZOPHENONE
• Synonyms: 4,4'-DI-T-BUTYLBENZOPHENONE;4,4'-DI-TERT-BUTYLBENZOPHENONE;BIS-(4-TERT-BUTYL-PHENYL)-METHANONE;4,4'-Di-butylbenzophenone;is-(4-tert-butyl-phenyl)-Methanone;Methanone, bis[4-(1,1-dimethylethyl)phenyl]-;4,4'-Di-tert-butylbenzophenone
• CAS NO: 15796-82-4
• Molecular Formula: C₂₁H₂₆O
• Molecular Weight: 294.43
• Mol File: 15796-82-4.mol
• Article Data: 28

Chemical Properties

• Melting Point: 132.0 to 136.0 °C
• Boiling Point: 158°C/1mmHg(lit.)
• Flash Point: 169.3 °C
• Appearance: Off-white crystalline
• Density: 0.978 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4,4'-DI-TERT-BUTYLBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-DI-TERT-BUTYLBENZOPHENONE(15796-82-4)
• EPA Substance Registry System: 4,4'-DI-TERT-BUTYLBENZOPHENONE(15796-82-4)

Safety Data

• Hazardous Substances Data: 15796-82-4(Hazardous Substances Data)

Usage

General Description

4,4'-di-tert-butylbenzophenone is a chemical compound that belongs to the family of benzophenones. It is a derivative of benzophenone, which is widely used in the production of sunscreen and other cosmetic products as a UV filter due to its ability to absorb UV light. The 4,4'-di-tert-butylbenzophenone variant is specifically known for its high photostability, making it particularly suitable for use in sunscreens and other products that require long-lasting UV protection. Additionally, it is often used as a photoinitiator in the production of various plastics and adhesives due to its ability to initiate polymerization reactions when exposed to light. However, it is important to handle this chemical with care, as it is considered to be a skin and eye irritant and may have harmful effects on aquatic organisms if released into the environment.

Upstream product

• 56-23-5 tetrachloromethane 
• 253185-03-4 tert-butylbenzene 
• 75-44-5 phosgene 
• 21655-77-6 1,1-bis-(4-tert-butyl-phenyl)-2,2-dichloro-ethene 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 52866-85-0 4-tert-butylphenyllithium 
• 98-73-7 4-(1,1-dimethylethyl)benzoic acid 
• 22679-54-5 4-tert-butylbenzophenone 
• 594-19-4 tert.-butyl lithium 
• 78828-12-3 Bis-(p-tert.-butyl-phenyl)dichloromethane 
• 201230-82-2 carbon monoxide 
• 58377-39-2 bis(4-tert-butylphenyl)iodonium bromide 
• 125016-82-2 4-chlorophenylbis(4-t-butylphenyl)methyl chloride 
• 3972-65-4 1-bromo-4-tert-butylbenzene 

Downstream Products

• 16607-60-6 bis(4-(tert-butyl)phenyl)methanol 
• 122336-12-3 1,1-bis-(4-tert-butyl-phenyl)-2-(4-chloro-phenyl)-ethene 
• 78828-12-3 Bis-(p-tert.-butyl-phenyl)dichloromethane 
• 78525-37-8 1,1,2,2-tetrakis(4-(tert-butyl)phenyl)ethene 
• 805948-14-5 4-Dimethylamino-1,1-bis-<4-tert-butyl-phenyl>-butanol-(1) 
• 58405-32-6 C₄₈H₇₀O₂Si₂ 
• 149064-67-5 1-(2'-pyridyl)-1,1-di((4''-tert-butyl)phenyl)methanol 
• 64918-93-0 1-tert-butyl-4-[1-(4-tert-butylphenyl)ethenyl]benzene 
• 133708-66-4 1,1,4,4-tetrakis(4-t-butylphenyl)-2-butyne-1,4-diol 
• 6934-33-4 tris(4-(tert-butyl)phenyl)methanol 
• 163233-80-5 1,4-Bisbenzene 
• 136575-86-5 {5-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4-dimethyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 
• 136575-97-8 {3-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4,6-trimethyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 
• 136575-92-3 {5-[Bis-(4-tert-butyl-phenyl)-hydroxy-methyl]-2,4-diisopropyl-phenyl}-bis-(4-tert-butyl-phenyl)-methanol 

Relevant articles and documents

Shuttle arylation by Rh(I) catalyzed reversible carbon–carbon bond activation of unstrained alcohols

The advent of transfer hydrogenation and borrowing hydrogen reactions paved the way to manipulate simple alcohols in previously unthinkable manners and circumvented the need for hydrogen gas. Analogously, transfer hydrocarbylation could greatly increase the versatility of tertiary alcohols. However, this reaction remains unexplored because of the challenges associated with the catalytic cleavage of unactivated C–C bonds. Herein, we report a rhodium(I)-catalyzed shuttle arylation cleaving the C(sp2)–C(sp3) bond in unstrained triaryl alcohols via a redox-neutral β-carbon elimination mechanism. A selective transfer hydrocarbylation of substituted (hetero)aryl groups from tertiary alcohols to ketones was realized, employing benign alcohols as latent C-nucleophiles. All preliminary mechanistic experiments support a reversible β-carbon elimination/migratory insertion mechanism. In a broader context, this novel reactivity offers a new platform for the manipulation of tertiary alcohols in catalysis.

A palladium-catalyzed C-H functionalization route to ketones: Via the oxidative coupling of arenes with carbon monoxide

We describe the development of a new palladium-catalyzed method to generate ketones via the oxidative coupling of two arenes and CO. This transformation is catalyzed by simple palladium salts, and is postulated to proceed via the conversion of arenes into high energy aroyl triflate electrophiles. Exploiting the latter can also allow the synthesis of unsymmetrical ketones from two different arenes.

Cercosporin-bioinspired selective photooxidation reactions under mild conditions

The development of an efficient system for selective oxidation of organic compounds to generate more valuable compounds with molecular oxygen is a significant challenge in industrial chemistry. Bioinspired by the ability of naturally occurring perylenequinonoid pigments (PQPs) to generate reactive oxygen species (ROS) upon photoirradiation, here we report that cercosporin, one of the perylenequinonoid pigments, can function as a cost-effective and environmentally friendly photocatalyst for a wide range of selective oxidations, including benzylic C-H bonds to carbonyls, amines to aldehydes, and sulfides to sulfoxides. All of the representative reactions proceeded smoothly with high efficiency under mild conditions. Owing to the use of inexpensive metal-free visible light-driven photocatalyst produced from microbial fermentation with cheap glucose as the starting material and the ease of handling, we expect that this developed method will be particularly attractive for many more applications in synthetic transformation.