158076-68-7

Basic information

• Product Name: 4HYDROXY2234556HEPTACHLOROBIPHENYL
• Synonyms: 4HYDROXY2234556HEPTACHLOROBIPHENYL
• CAS NO: 158076-68-7
• Molecular Formula: C12H3Cl7O
• Molecular Weight: 411.32262
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Isotope Labelled Compounds;Aromatics, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 158076-68-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 406.3°Cat760mmHg
• Flash Point: 199.5°C
• Appearance: /
• Density: 1.736g/cm³
• CAS DataBase Reference: 4HYDROXY2234556HEPTACHLOROBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 4HYDROXY2234556HEPTACHLOROBIPHENYL(158076-68-7)
• EPA Substance Registry System: 4HYDROXY2234556HEPTACHLOROBIPHENYL(158076-68-7)

Safety Data

• Hazardous Substances Data: 158076-68-7(Hazardous Substances Data)

Usage

Description

4HYDROXY2234556HEPTACHLOROBIPHENYL is a hydroxylated polychlorinated biphenyl metabolite that has been detected in the serum of both wildlife and humans. It is a compound with significant environmental and health implications due to its presence in various ecosystems and its potential effects on thyroid hormone levels.

Uses

Used in Environmental Monitoring:
4HYDROXY2234556HEPTACHLOROBIPHENYL is used as a biomarker for assessing the exposure of wildlife and humans to polychlorinated biphenyls (PCBs). Its detection in serum samples helps in understanding the extent of PCB contamination in the environment and the potential health risks associated with it.
Used in Endocrine Disruption Studies:
In the field of endocrinology, 4HYDROXY2234556HEPTACHLOROBIPHENYL is used as a test compound to study its effects on the level of serum thyroid hormones in mice. This helps researchers understand the potential endocrine-disrupting properties of this metabolite and its implications for thyroid function and overall health.
Used in Toxicology Research:
4HYDROXY2234556HEPTACHLOROBIPHENYL is utilized in toxicology research to investigate the potential toxic effects of PCB metabolites on various biological systems. This includes studying its impact on cellular processes, organ function, and overall health outcomes in exposed organisms.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, due to its potential endocrine-disrupting properties, 4HYDROXY2234556HEPTACHLOROBIPHENYL could be used in the pharmaceutical industry as a compound of interest for developing drugs or therapies targeting endocrine-related disorders. Further research would be required to explore this application.

Upstream product

• 634-83-3 2,3,4,5-tetrachloroaniline 
• 50375-10-5 1,2,4-trichloro-3-methoxybenzene 

Relevant articles and documents

Synthesis and characterization of hydroxylated polychlorinated biphenyls (PCBs) identified in human serum

Hydroxylated polychlorinated biphenyls (PCBs) have been identified in wildlife and human samples. Most of these compounds are highly chlorinated (penta-hepatachloro) and contain a single meta- or para-hydroxyl group. Using the Cadogan coupling procedure, the following hydroxy-PCBs congeners were synthesized: 2,3,3',4',5-pentachloro-4-biphenylol, 2,3',4,4',5-pentachloro-3-biphenylol, 2',3,3',4',5-pentachloro-4-biphenylol, 2,2',3',4,4'-pentachloro-3-biphenylol, 2,2',3,3',4',5-pentachloro-4-biphenylol, 2,2',3',4,4',5-hexachloro-3-biphenylol, 2,2',3,4',5,5'-hexachloro-4-biphenylol, 2,2',3,3',4',5,5'-heptachloro-4-biphenyl 2,2',3',4,4',5,5'-heptachloro-3-biphenylol, 2,2',3,4',5,5',6-heptachloro-4-biphenylol. Many of these compounds have been detected as residues in human serum and current studies are investigating their activities as agonists and antagonists for several endocrine-mediated responses.