158846-98-1

Basic information

• Product Name: Uridine, 3'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-dideoxy-
• CAS NO: 158846-98-1
• Molecular Formula: C30H29N5O6
• Molecular Weight: 555.59
• Mol File: 158846-98-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Uridine, 3'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-dideoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Uridine, 3'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-dideoxy-(158846-98-1)
• EPA Substance Registry System: Uridine, 3'-azido-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2',3'-dideoxy-(158846-98-1)

Safety Data

• Hazardous Substances Data: 158846-98-1(Hazardous Substances Data)

Upstream product

• 117560-95-9 Methanesulfonic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 23669-79-6 DMT-dU 
• 170236-36-9 5'-O-(4,4'-dimethoxytrityl)-2,3'-anhydro-2'-deoxyuridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 84472-85-5 Navuridine 
• 951-78-0 2'-deoxyuridine 

Downstream Products

• 184241-35-8 1-{(2R,4S,5S)-4-Azido-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-4-(2-nitro-phenoxy)-1H-pyrimidin-2-one 
• 170236-33-6 3'-azido-N₄-benzoyl-5'-O-(4,4'-dimethoxytrityl)-2',3'-dideoxycytidine 
• 184241-37-0 4-Amino-1-{(2R,4S,5S)-4-azido-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidin-2-one 

Relevant articles and documents

New carbamate supports for the preparation of 3'-amino-modified oligonucleotides

A novel approach for the preparation of oligonucleotides carrying amino groups at the 3'-end is described. Several CPG supports having aminoalkyl groups and 3'-amino-2',3'-dideoxynucleosides linked through base-labile carbamate linkages such as 2-(2- nitrophenyl)ethoxycarbonyl and fluorenylmethoxycarbonyl were prepared using two different strategies. These supports are compatible to the standard solid phase phosphite-triester methodology and yield oligonucleotides containing amino groups at the 3'-end. Several properties of the 3'-amino oligonucleotides, such as nuclease resistance, hybridization, and preparation of oligonucleotide conjugates are discussed.