158878-47-8

Basic information

• Product Name: CERIVASTATIN LACTONE
• Synonyms: CERIVASTATIN LACTONE
• CAS NO: 158878-47-8
• Molecular Formula: C26H32FNO4
• Molecular Weight: 441.53
• Mol File: 158878-47-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: CERIVASTATIN LACTONE(CAS DataBase Reference)
• NIST Chemistry Reference: CERIVASTATIN LACTONE(158878-47-8)
• EPA Substance Registry System: CERIVASTATIN LACTONE(158878-47-8)

Safety Data

• Hazardous Substances Data: 158878-47-8(Hazardous Substances Data)

Usage

Description

Cerivastatin lactone is a metabolite derived from Cerivastatin, which is a competitive inhibitor of HMG-CoA reductase. It possesses the ability to inhibit CYP3A4/5 activity, making it a potentially useful compound in various applications.

Uses

Used in Pharmaceutical Industry:
Cerivastatin lactone is used as an inhibitor for CYP3A4/5 activity to modulate the metabolism of certain drugs, potentially improving their efficacy and reducing side effects. Its inhibitory effects on these enzymes can be beneficial in managing drug interactions and optimizing pharmacological treatments.
Used in Research Applications:
In the field of research, Cerivastatin lactone serves as a valuable tool for studying the role of CYP3A4/5 enzymes in drug metabolism and their involvement in various physiological and pathological processes. This can contribute to the development of new drugs and therapies targeting these enzymes.