15894-04-9 Usage
Description
4-Fluorobenzyl mercaptan is an organic compound characterized by the presence of a sulfur atom bonded to a benzene ring with a fluorine atom at the para position. It is known for its unique chemical properties and reactivity, which make it a versatile building block in various chemical syntheses.
Uses
Used in Pharmaceutical Industry:
4-Fluorobenzyl mercaptan is used as a synthetic intermediate for the production of fluorapacin degradation products, such as bis(4-fluorobenzyl)disulfide and bis(4-fluorobenzyl)tetrasulfide. These compounds have potential applications in the development of new pharmaceuticals, particularly in the field of antibiotics.
Used in Chemical Synthesis:
In the field of organic chemistry, 4-Fluorobenzyl mercaptan is used as a reagent in the synthesis of various organic compounds. For instance, it undergoes a reaction with p-chloranil to afford mainly 2,5-dichloro-3,6-S-disubstituted benzoquinone and 2,6-dichloro-3,5-S-disubstituted benzoquinone. These synthesized products can be further utilized in the development of novel chemical compounds with potential applications in various industries.
Overall, 4-Fluorobenzyl mercaptan is a valuable compound with applications in the pharmaceutical industry and organic chemistry, showcasing its importance in the synthesis of various compounds and its potential in the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 15894-04-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,8,9 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 15894-04:
(7*1)+(6*5)+(5*8)+(4*9)+(3*4)+(2*0)+(1*4)=129
129 % 10 = 9
So 15894-04-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H8FNO/c1-6-4-10(13)8-5-7(11)2-3-9(8)12-6/h2-5H,1H3,(H,12,13)
15894-04-9Relevant articles and documents
Reactions of Arylmethanethiols with 1,4-Disubstituted 1,3-Butadiynes
Freeman, Fillmore,Lu, Hengyao,Zeng, Qingbei
, p. 4350 - 4354 (1994)
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Phosphorus Pentasulfide Mediated Conversion of Primary Carbamates into Thiols
Maurya, Chandra Kant,Gupta, Pradeep Kumar
, p. 1649 - 1651 (2017/08/11)
In this paper, we report a method for the conversion of primary carbamates into thiols in the presence of phosphorus pentasulfide (P 2 S 5) in refluxing toluene. Presently, no method exists in the literature for conversion of carbamates into thiols and, to the best of our knowledge, it is the first report for this type of conversion. This method presents an indirect route for the conversion of alcohols into thiols via their carbamate derivatives that may be useful in the total synthesis of compounds containing a thiol functionality.
Preparation and in-vitro evaluation of 4-benzylsulfanylpyridine-2- carbohydrazides as potential antituberculosis agents
Herzigova, Petra,Klimesova, Vera,Palat, Karel,Kaustova, Jarmila,Dahse, Hans-Martin,Moellmann, Ute
body text, p. 394 - 404 (2009/11/30)
A set of 4-benzylsulfanylpyridine-2-carbohydrazides was synthesized and evaluated for in vitro antimycobacterial activity against Mycobacterium tuberculosis, non-tuberculous mycobacteria, and multidrug-resistant M. tuberculosis. The activities expressed as the minimum inhibitory concentration (MIC) fall into a range of 2 to 125 μmol/L, most often 4 to 32 μmol/L. The results revealed that the substituents on the benzyl moiety do not influence the antimycobacterial efficacy. The substances exhibited similar activities against sensitive and resistant strains of M. tuberculosis. Furthermore, compounds show low antiproliferative effect and cytotoxicity.
