15959-53-2

Basic information

• Product Name: N-Phenylsulfamide
• Synonyms: N-Phenylsulfamide
• CAS NO: 15959-53-2
• Molecular Formula: C₆H₈N₂O₂S
• Molecular Weight: 172.2
• Mol File: 15959-53-2.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-Phenylsulfamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-Phenylsulfamide(15959-53-2)
• EPA Substance Registry System: N-Phenylsulfamide(15959-53-2)

Safety Data

• Hazardous Substances Data: 15959-53-2(Hazardous Substances Data)

Upstream product

• 20619-96-9 μ-imido-disulfuric acid dianilide 
• 63489-51-0 acetyl-phenyl-sulfamoyl chloride 
• 62-53-3 aniline 
• 49689-92-1 N-tert-Butyl-N'-phenyl-sulfamid 
• 110-89-4 piperidine 
• 1189-71-5 isocyanate de chlorosulfonyle 
• 104-94-9 4-methoxy-aniline 
• 107-85-7 1-amino-3-methylbutane 
• 5631-35-6 1-[4,4-bis(4-fluorophenyl)butyl]piperazine 
• 100-46-9 benzylamine 
• 371-40-4 4-fluoroaniline 
• 153028-13-8 N-(tert-butoxycarbonyl)-N'-(phenyl)sulfamide 
• 108-86-1 bromobenzene 
• 591-50-4 iodobenzene 

Downstream Products

• 20619-96-9 μ-imido-disulfuric acid dianilide 
• 130669-78-2 3,7-Diphenyl-2,6,1,3,5,7-dithiatetraazabicyclo<3.3.1>nonane 
• 122172-65-0 3,4-Diamino-1,1-dioxo-2-phenyl-1H-1λ⁶-[1,2,5]thiadiazol-2-ium; chloride 
• 133116-78-6 ethyl 2,2-dioxo-3,4-dihydro-2,1,3-benzothiadiazin-4-ylacetate 
• 133116-74-2 ethyl 4-carbethoxy-2-phenyl-1,1-dioxo-5,6-dihydro-2H-1,2,6-thiadiazin-5-ylacetate 
• 106687-41-6 5-methyl-2-phenyl-1,2,6-thiadiazin-3(2H,6H)-one 1,1-dioxide 
• 118025-37-9 N-acetoacetyl-N'-phenylsulfamide 
• 117320-54-4 5-methyl-6-phenyl-1,2,6-thiadiazin-3(2H,6H)-one 1,1-dioxide 
• 106350-13-4 4-amino-2-phenyl-2,3-dihydro-3-oxo-1,2,5-thiadiazole 1,1-dioxide 
• 122172-55-8 4-amino-2,3-dihydro-3-imino-2-phenyl-1,2,5-thiadiazole 1,1-dioxide 
• 115347-04-1 5-amino-2-phenyl-2H-1,2,6-thiadiazine-3(4H)-one 1,1-dioxide 
• 401907-24-2 1-phenethyl-3-(4-sulfamoylbenzyl)urea 
• 401907-25-3 1-(4-t-butylbenzyl)-3-(4-sulfamoylbenzyl)thiourea 
• 936756-41-1 2-phenyl-3-methyl-1,1-dioxo-1,2,6-thiadiazine-5-carboxylic acid ethyl ester 

Relevant articles and documents

Synthesis and antitumor evaluation of novel sulfonylcycloureas derived from nitrogen mustard

A new series of sulfonylcycloureas derivatives have been synthesized and evaluated in vitro for their antitumor activity against four cancer cell lines (A431, Jurkat, U266, and K562). These compounds were prepared by the condensation of several sulfonamides (2am) with ethyl bis(2-chloroethyl)carbamate (1a). The relative cytotoxicity of these new derivatives in comparison to chlorambucil is reported.

Convenient Synthesis of Novel N -Acylsulfonamides Containing Phosphonate Moiety

The present study describes a convenient method for the synthesis of new N-acylsulfonamides containing phosphonate moiety. The N-acylsulfonamides were prepared starting from chlorosulfonyl isocyanate (CSI) in four steps (carbamoylation, sulfamoylation, deprotection, and acylation). Trimethylphosphite has been used to introduce the phosphonate moiety into N-acylsulfonamides via Arbuzov reaction. GRAPHICAL ABSTRACT

An efficient method for the synthesis of novel n-acylsulfonamides using tin (IV) chloride as catalysts

A series of novel N-acylsulfonamides derivatives were synthesized via direct condensation of parent sulfonamide with ethyl lactate as an acylating agent in the presence of tin (IV) chloride (SnCl4) as a Lewis acid catalyst. The sulfonamides were prepared, starting from chlorosulfonyl isocyanate (CSI), in three steps (carbamoylation, sulfamoylation, and deprotection) with excellent yields. Copyright