159689-43-7

Basic information

• Product Name: 4-(pentafluoro-λ⁶-sulfanyl)phenyl isocyanate
• Synonyms: 4-(pentafluoro-λ⁶-sulfanyl)phenyl isocyanate
• CAS NO: 159689-43-7
• Molecular Weight: 245.173
• Mol File: 159689-43-7.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-(pentafluoro-λ⁶-sulfanyl)phenyl isocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(pentafluoro-λ⁶-sulfanyl)phenyl isocyanate(159689-43-7)
• EPA Substance Registry System: 4-(pentafluoro-λ⁶-sulfanyl)phenyl isocyanate(159689-43-7)

Safety Data

• Hazardous Substances Data: 159689-43-7(Hazardous Substances Data)

Upstream product

• 5634-37-7 di-(2,2,2-trichloroethyl)-carbonate 
• 2993-24-0 4-(pentafluorosulfanyl)aniline 
• 2613-27-6 1-nitro-4-(pentafluorosulfanyl)benzene 
• 32315-10-9 bis(trichloromethyl) carbonate 

Relevant articles and documents

Carbazole-based bis-ureas and thioureas as electroneutral anion transporters

We report a series of easily accessible carbazole-based bis-ureas and thioureas as effective anion receptors and transporters. The compounds exhibit moderate Cl? binding affinity in wet DMSO and Cl? transport capabilities in phospholipid membranes predominantly through an electroneutral H+/Cl? and anion exchange mechanisms.

HRI ACTIVATORS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES

New compounds of formula (I) are provided,wherein: X is CH or N, preferably CH; n is 1-5, preferably 1-2; m is 0-5, preferably 1-2; and, when m is 2-5, two of the R2 radicals taken together with two adjacent carbons of the benzene ring can form a 5- or 6-membered heterocyclic ring fused with the benzene ring. Compounds (I) are heme-regulated inhibitor (HRI) activators and useful for the prevention or treatment of cardiometabolic diseases such as metabolic syndrome, obesity, insulin resistance, type 2 diabetes mellitus, non-alcoholic fatty liver disease, steatosis, non-alcoholic steatohepatitis, hypertension, dyslipidemia, atherosclerosis, and heart disease.

Synthesis of some arylsulfur pentafluoride pesticides and their relative activities compared to the trifluoromethyl analogues

Examples of pesticides containing an arylsulfur pentafluoride group were made and their biological activities compared to the corresponding trifluoromethyl analogues. A phenylsulfur pentafluoride analogue of the insecticide fipronil, screened against a resistant strain of Musca domestica, showed higher activity than the corresponding trifluoromethyl analogue.