15986-92-2

Basic information

• Product Name: 2,3-dihydro-5,6-dimethylpyrazine
• Synonyms: 2,3-dihydro-5,6-dimethylpyrazine;2,3-Dimethyl-5,6-dihydropyrazine;5,6-Dihydro-2,3-dimethylpyrazine;5,6-Dimethyl-2,3-dihydropyrazine;DHDMP;DHP-1;Einecs 240-122-3
• CAS NO: 15986-92-2
• Molecular Formula: C₆H₁₀N₂
• Molecular Weight: 110.157
• EINECS: 240-122-3
• Mol File: 15986-92-2.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 173.2°Cat760mmHg
• Flash Point: 49.8°C
• Appearance: /
• Density: 1.02g/cm³
• Vapor Pressure: 1.71mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 6.73±0.20(Predicted)
• CAS DataBase Reference: 2,3-dihydro-5,6-dimethylpyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dihydro-5,6-dimethylpyrazine(15986-92-2)
• EPA Substance Registry System: 2,3-dihydro-5,6-dimethylpyrazine(15986-92-2)

Safety Data

• Hazardous Substances Data: 15986-92-2(Hazardous Substances Data)

Usage

Description

2,3-dihydro-5,6-dimethylpyrazine is an organic compound with the molecular formula C6H10N2. It is a colorless to pale yellow liquid with a strong, earthy, and musty odor. 2,3-dihydro-5,6-dimethylpyrazine is known for its ability to enhance and prolong the intensity of fragrances, making it a valuable component in the perfume industry.

Uses

Used in Perfumery:
2,3-dihydro-5,6-dimethylpyrazine is used as a fragrance modulator for increasing and prolonging the intensity of fragrances. Its unique earthy and musty scent contributes to the overall complexity and depth of perfume compositions.
Used in Perfume Composition Studies:
In the field of perfume composition, 2,3-dihydro-5,6-dimethylpyrazine is used as a key component in studies involving the development of new fragrance modulator compounds and silicic acid esters. These studies aim to create more effective and longer-lasting fragrances by understanding the interactions between various compounds and their impact on the overall scent profile.

InChI:InChI=1/C6H10N2/c1-5-6(2)8-4-3-7-5/h3-4H2,1-2H3

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Relevant articles and documents

Formation of tricyclic heterocycles from the condensation reaction of 1,2-diamines with 1,2-diketones

Condensation of 1,2-diamines with 1,2-diketones yielded unexpected tricyclic heterocycles. The structures were determined by single-crystal X- ray analysis.

New compounds derived from dihydropyrazines having DNA strand-breakage activity

Dihydropyrazine derivatives such as 2,3-dihydro-5,6-dimethylpyrazine (1), 2,3-dihydro-2,5,6-trimethylpyrazine (2) and 2,3-dihydro-2,2,5,6- teramethylpyrazine (3) were found to be transformed into (2R*, 3S*, 5R*)- 1,2 ethylene-imino-1,7,10-triaza-2,3,6-trimethyl-3-hydroxy-spiro [4,5] decan- 6-ene (4), the stereoisomeric mixtures of 2,4aR*,7,9aS* - tetramethylcyclohexano [1,2-e: 4,5-e']-dipiperazin-6-ene (5) and (4aR*, 9aS*)-2,2,4a,7,7,9a-hexamethylcyclohexano [1,2-e: 4,5-e']-dipiperazin-6-ene (6), respectively. These dimerized compounds (4, 5 and 6), whose structures were determined by X-ray and nmr spectral analyses, showed almost the same DNA strand-breakage activity as their parent dihydropyrazines. The dimerization pathway is discussed on the basis of the PM3 calculation data.

A reusable zirconium(IV) Schiff base complex catalyzes highly efficient synthesis of quinoxalines under mild conditions

A zirconium(IV) complex of a bidentate Schiff base (ZrL2Cl 2) has been synthesized by the reaction of (z)-N-benzylidene-2- hydroxypropane-1-amine (HL) and ZrCl4. Spectroscopic data and elemental analyses are consistent with a monomeric complex with a ligand:Zr ratio of 2:1. The catalytic activity of ZrL2Cl2 has been investigated for the efficient synthesis of a wide variety of quinoxaline derivatives under mild conditions. The employment of ethanol as an environmentally benign solvent in this high yield method, along with high turnover numbers and reusability of the catalyst providing ready scalability, makes it appropriate for practical applications.

Phenyl-substituted dihydropyrazines with DNA strand-breakage activity

Monophenyl-substituted dihydropyrazines (Ph-DHP-1 to 4) of 2,3-dihydro-5,6-dimethylpyrazine (Me-DHP-1), which have the inductive effects of apoptosis and mutagenesis, were synthesized and their biological effect was investigated in terms of DNA strand-breakage. Differences between the phenyl- and methyl-substituted dihydropyrazines were examined.