16000-39-8

Basic information

• Product Name: 2-METHOXY-1-NAPHTHONITRILE
• Synonyms: 1-Naphthalenecarbonitrile, 2-methoxy-;1-Naphthonitrile, 2-methoxy-;2-Methoxy-1-naphthalenecarbonitrile;1-CYANO-2-METHOXYNAPHTHALENE;2-METHOXY-1-NAPHTHONITRILE;1-Cyano-2-methoxynaphtalene;2-Methoxy-1-naphthonitrile,98%;2-Methoxy-1-naphthonitrile1-Cyano-2-methoxynaphtalene
• CAS NO: 16000-39-8
• Molecular Formula: C₁₂H₉NO
• Molecular Weight: 183.21
• EINECS: 240-133-3
• Product Categories: Naphthalene derivatives
• Mol File: 16000-39-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 95-96 °C(lit.)
• Boiling Point: 316.88°C (rough estimate)
• Flash Point: 153ºC
• Appearance: white to brown crystals or crystalline powder
• Density: 1.1261 (rough estimate)
• Vapor Pressure: 1.89E-05mmHg at 25°C
• Refractive Index: 1.5880 (estimate)
• CAS DataBase Reference: 2-METHOXY-1-NAPHTHONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-1-NAPHTHONITRILE(16000-39-8)
• EPA Substance Registry System: 2-METHOXY-1-NAPHTHONITRILE(16000-39-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• WGK Germany: 3
• Hazardous Substances Data: 16000-39-8(Hazardous Substances Data)

Usage

Chemical Properties

white to brown crystals or crystalline powder

InChI:InChI=1/C12H9NO/c1-14-12-7-6-9-4-2-3-5-10(9)11(12)8-13/h2-7H,1H3

Upstream product

• 506-68-3 bromocyane 
• 93-04-9 2-Methoxynaphthalene 
• 99806-91-4 2‐methoxy‐1‐naphthaldoxime 
• 108-24-7 acetic anhydride 
• 5392-12-1 2-methoxy-1-naphthaldehyde 
• 143-33-9 sodium cyanide 
• 98606-61-2 N-[1-(2-Methoxy-naphthalen-1-yl)-meth-(E)-ylidene]-N'-phenyl-hydrazine 
• 68-12-2 N,N-dimethyl-formamide 
• 151-50-8 potassium cyanide 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 
• 3401-47-6 1-bromo-2-methoxynaphthalene 
• 931-97-5 1-hydroxy-1-cyclohexanecarbonitrile 
• 947-62-6 2-methoxy-1-naphthoic acid 

Downstream Products

• 1130-80-9 2-methoxy-1-methylnaphthalene 

Relevant articles and documents

Lewis Acid-Mediated Cyanation of Phenols Using N-Cyano-N-phenyl-p-toluenesulfonamide

Lewis acid-mediated cyanation of phenol derivatives with N-cyano-N-phenyl-p-toluenesulfonamide (NCTS) has been developed. The reaction proceeded efficiently with high regioselectivity to produce aromatic nitriles in moderate to excellent yields, which provides a direct and practical access to valuable products. (Figure presented.).

Electrochemical C-H cyanation of electron-rich (Hetero)arenes

A straightforward method for the electrochemical C-H cyanation of arenes and heteroarenes that proceeds at room temperature in MeOH, with NaCN as the reagent in a simple, open, undivided electrochemical cell is reported. The platinum electrodes are passivated by ad-sorbed cyanide, which allows conversion of an exceptionally broad range of electron-rich substrates all the way down to dialkyl arenes. The cyanide electrolyte can be replenished with HCN, opening opportunities for salt-free industrial C-H cyanation.

Electroorganic synthesis of nitriles via a halogen-free domino oxidation-reduction sequence

A direct electroorganic sequence yielding nitriles from oximes in undivided cells is reported. Despite the fact that intermediate nitrile oxides might be formed, the method is viable to prepare benzonitriles without substituents ortho to the aldoxime moiety. This constant current method is easy to perform for a broad scope of substrates and employs common electrodes, such as graphite and lead.