160592-66-5Relevant articles and documents
Crystal form of phenol derivative and preparation method of crystal form
-
Paragraph 0072; 0073; 0074; 0075; 0076; 0077; 0078; 0079, (2017/04/21)
The invention provides a crystal form of a phenol derivative and a preparation method of the crystal form and in particular provides a crystal form of a compound shown as the formula (I) and an isomer thereof, a preparation method and application of the crystal form to the medicine field. A structure is shown as the description.
Process for producing ortho-isopropylated phenol derivatives
-
, (2008/06/13)
This invention relates to the process for producing ortho-isopropylated phenol derivatives having following general formula (VIII). STR1 (in the above formula, R1 is a hydrogen or a low alkyl group of C1 -C4) A process for producing ortho-isopropylated phenol derivatives (VIII) of the present invention is characterized by obtaining position isomer desired by means of Claisen rearrangement of phenyl allyl ether without catalyst in atmosphere, and then obtaining only one isomer by oxidation and reduction of the above-obtained position isomer. According to the present invention, ortho-alkylated phenol derivatives (VIII) having high purity at low temperature and low pressure can be prepared without producing a by-product and requirement of the complicated separation procedure.