16066-32-3

Basic information

• Product Name: Morpholine, 4-(phenylsulfinyl)-
• CAS NO: 16066-32-3
• Molecular Formula: C10H13NO2S
• Molecular Weight: 211.285
• Mol File: 16066-32-3.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Morpholine, 4-(phenylsulfinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Morpholine, 4-(phenylsulfinyl)-(16066-32-3)
• EPA Substance Registry System: Morpholine, 4-(phenylsulfinyl)-(16066-32-3)

Safety Data

• Hazardous Substances Data: 16066-32-3(Hazardous Substances Data)

Upstream product

• 4837-31-4 4-Phenylsulfanyl-morpholine 
• 873-55-2 sodium benzenesulfonate 
• 5765-65-1 4-(benzoyloxy)morpholine 
• 16066-31-2 benzenesulfinamide 
• 110-91-8 morpholine 
• 4972-29-6 benzenesulphinyl chloride 
• 108-98-5 thiophenol 
• 51010-74-3 morpholinosulfur trifluoride 
• 98-80-6 phenylboronic acid 
• 670-98-4 methyl benzenesulfinate 
• 931-59-9 benzenesulfenyl chloride 

Downstream Products

• 5033-21-6 4-benzenesulfonylmorpholine 
• 1394013-36-5 4-(S-phenylsulfonimidoyl)morpholine 

Relevant articles and documents

Direct Synthesis of Sulfinamides by the Copper-Catalyzed Electrophilic Amidation of Sulfenate Anions

A method for the construction of sulfinamides via the copper-catalyzed electrophilic amination of sulfenate anions using N-benzoyloxyamines as the amination reagents. This procedure featured with the capture of in-situ generated sulfenate anions from β-sulfinyl esters under mild conditions, which provides an efficient strategy for the synthesis of diverse sulfinamides in moderate to good yields. (Figure presented.).

Copper-Catalyzed Transsulfinamidation of Sulfinamides as a Key Step in the Preparation of Sulfonamides and Sulfonimidamides

Secondary or tertiary sulfinamides are prepared by copper-catalyzed transsulfinamidation of primary sulfinamides with O-benzoyl hydroxylamines. Subsequent oxidations of the resulting products lead to the corresponding sulfonamides. Treatment of N-aryl sulfinamides with O-benzoyl hydroxylamines under copper catalysis provides N-aryl sulfonimidamides.

Metal-Free Cross-Coupling of Arylboronic Acids and Derivatives with DAST-Type Reagents for Direct Access to Diverse Aromatic Sulfinamides and Sulfonamides

We have developed a simple and convenient method for the cross-coupling of arylboronic acids and their derivatives with DAST-type reagents under mild and metal-free conditions to directly afford sulfinamides in moderate to good yields. Moreover, sulfonamides were obtained after a simple oxidation reaction. The reaction mechanism was investigated by18O-labeling experiments, and the synthetic utility was demonstrated by the sulfoxidation of natural products.