160865-72-5

Basic information

• Product Name: (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl cinnamate
• Synonyms: (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl cinnamate
• CAS NO: 160865-72-5
• Molecular Weight: 286.414
• Mol File: 160865-72-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl cinnamate(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl cinnamate(160865-72-5)
• EPA Substance Registry System: (1S,2R,5S)-2-isopropyl-5-methylcyclohexyl cinnamate(160865-72-5)

Safety Data

• Hazardous Substances Data: 160865-72-5(Hazardous Substances Data)

Upstream product

• 2216-51-5 (-)-menthol 
• 102-92-1 cinnamoyl chloride 
• 108945-28-4 (1S,2R,5S)‐2‐isopropyl‐5‐methylcyclohexyl acrylate 
• 100-51-6 benzyl alcohol 

Downstream Products

• 114466-84-1 (2R,3R)-(+)-menthyl 2-amino-3-((S-3-nitro-2-pyridinesulfenyl)thio)-3-phenylpropionate 
• 114466-85-2 (2R,3R)-2-((tert-butyloxycarbonyl)amino)-3-((S-3-nitro-2-pyridinesulfenyl)thio)-3-phenylpropionic acid 
• 114529-89-4 (2R,3R)-(+)-menthyl 2-amino-3-((4-methoxybenzyl)thio)-3-phenylpropionate 
• 114529-88-3 cis-(2S,3S)-2-((+)-menthyloxycarbonyl)-3-phenylaziridine 

Relevant articles and documents

Mizoroki-Heck Reaction of Unstrained Aryl Ketones via Ligand-Promoted C-C Bond Olefination

Mizoroki-Heck reaction of unstrained aryl ketone with acrylate/styrene is accomplished via palladium-catalyzed ligand-promoted C-C bond cleavage. Various (hetero)aryl ketones are compatible in the reaction, affording the alkene product in good to excellent yields. Further applications in the late-stage olefination of some drugs, natural products, and fragrance-derived aryl ketones demonstrate the synthetic utility of this protocol. By employing ketone as both the directing group and the leaving group, 1,2-bifunctionalization is achieved via sequential ortho-C-H alkylation/ipso-Heck olefination.