1609567-93-2Relevant articles and documents
Unexpected beneficial effect of ortho -substituents on the (s)-proline-catalyzed asymmetric aldol reaction of acetone with aromatic aldehydes
Martínez, Alberto,Van Gemmeren, Manuel,List, Benjamin
supporting information, p. 961 - 964 (2014/05/06)
An intriguing effect of electronegative 2,6-substituents on the stereochemical outcome of (S)-proline-catalyzed aldol reactions between benzaldehyde derivatives and acetone is reported. Remarkably high enantioselectivities can be achieved with such substrates. Georg Thieme Verlag Stuttgart New York.