1611-57-0 Usage
Description
TERT-OCTYL ISOCYANATE, also known as 1,1,3,3-Tetramethylbutyl isocyanate, is a sterically hindered isocyanate compound derived from tert-octylamine. It possesses unique chemical properties that make it suitable for various applications in different industries.
Uses
Used in Chemical Synthesis:
TERT-OCTYL ISOCYANATE is used as a reagent for the synthesis of amides through the Grignard reaction. Its steric hindrance contributes to the selective formation of desired products in this reaction, making it a valuable component in organic chemistry.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TERT-OCTYL ISOCYANATE is used as a building block for the development of new drugs. Its unique chemical structure allows for the creation of novel compounds with potential therapeutic applications.
Used in Polymer Industry:
TERT-OCTYL ISOCYANATE is used as a monomer in the production of polyurethanes and other polymers. Its steric hindrance can lead to the formation of polymers with specific properties, such as improved thermal stability or enhanced mechanical strength.
Used in Coatings and Adhesives:
In the coatings and adhesives industry, TERT-OCTYL ISOCYANATE is used as a component in the formulation of high-performance products. Its chemical properties can contribute to improved adhesion, durability, and resistance to environmental factors.
Used in Surface Treatments:
TERT-OCTYL ISOCYANATE is used in surface treatments to provide specific properties to materials, such as increased water resistance or improved scratch resistance. Its unique chemical structure allows for tailored surface modifications.
Synthesis Reference(s)
Journal of the American Chemical Society, 78, p. 4538, 1956 DOI: 10.1021/ja01599a008
Check Digit Verification of cas no
The CAS Registry Mumber 1611-57-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,1 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1611-57:
(6*1)+(5*6)+(4*1)+(3*1)+(2*5)+(1*7)=60
60 % 10 = 0
So 1611-57-0 is a valid CAS Registry Number.
1611-57-0Relevant articles and documents
COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF CANCERS
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Paragraph 00177, (2014/07/08)
The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.
Preparation of isocyanates from primary amines and carbon dioxide using Mitsunobu chemistry
Saylik, Dilek,Horvath, Michael J.,Elmes, Patricia S.,Jackson, W. Roy,Lovel, Craig G.,Moody, Keith
, p. 3940 - 3946 (2007/10/03)
Primary alkylamines 1 and hindered arylamines 1 give high yields of isocyanates 5 when reacted with carbon dioxide and the Mitsunobu zwitterions 4 generated from dialkyl azodicarboxylates and Bu3P in dichloromethane at - 78°C. Use of Ph3P still gave high yields of isocyanates from reactions of primary alkylamines, but only low yields were obtained from reactions of aromatic amines. Reactions which failed to give high yields of isocyanates gave either carbamoylhydrazines 6 and/or dicarbamoylhydrazines 10 and/or triazolinones 7. The triazolinones were shown to arise from reactions of reactive aryl isocyanates with the Mitsunobu zwitterion. The carbamoylhydrazines were shown not to arise from reaction of isocyanate with reduced dialkyl azodicarboxylates, and a mechanism for their formation is proposed. Single-crystal X-ray analyses confirmed the structures of 6, 7, and 10.
Neue Methode zur Synthese von Isocyanaten unter milden Bedingungen
Knoelker, Hans-Joachim,Braxmeier, Tobias,Schlechtingen, Georg
, p. 2746 - 2749 (2007/10/03)
Keywords: Arendiyldiisocyanate; Di-tert-butyldicarbonat; 4-Dimethylaminopyridin; Isocyanate
