1611441-30-5

Basic information

• Product Name: C₂₄H₁₇ClN₂O₂
• Synonyms: C₂₄H₁₇ClN₂O₂
• CAS NO: 1611441-30-5
• Molecular Weight: 400.864
• Mol File: 1611441-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₁₇ClN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₁₇ClN₂O₂(1611441-30-5)
• EPA Substance Registry System: C₂₄H₁₇ClN₂O₂(1611441-30-5)

Safety Data

• Hazardous Substances Data: 1611441-30-5(Hazardous Substances Data)

Upstream product

• 68769-69-7 2-((1H-indol-3-yl)methyl)isoindoline-1,3-dione 
• 1611441-11-2 2-((2-bromo-1H-indol-3-yl)methyl)isoindoline-1,3-dione 
• 145349-62-8 2-chlorophenyl-4-methylphenylboronic a cid 
• 87-52-5 3-(Dimethylaminomethyl)indole 
• 1074-82-4 potassium phtalimide 

Downstream Products

• 1611441-42-9 (2-(2-chloro-4-methylphenyl)-1-(methylsulfonyl)-1H-indol-3-yl)methanamine 
• 1611441-36-1 C₂₅H₁₉ClN₂O₄S 

Relevant articles and documents

Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold

Dipeptidyl peptidase IV (DPP4) inhibitors are proven in the treatment of type 2 diabetes. We designed and synthesized a series of novel indole compounds that selectively inhibit the activity of DPP4 over dipeptidyl peptidase 9 (DPP9) (>200 fold). We further co-crystallized DPP4 with indole sulfonamide (compound 1) to confirm a proposed binding mode. Good metabolic stability of the indole compounds represents another positive attribute for further development.