1615720-26-7

Basic information

• Product Name: C₁₉H₁₄N₄O₄S
• Synonyms: C₁₉H₁₄N₄O₄S
• CAS NO: 1615720-26-7
• Molecular Weight: 394.411
• Mol File: 1615720-26-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₄N₄O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₄N₄O₄S(1615720-26-7)
• EPA Substance Registry System: C₁₉H₁₄N₄O₄S(1615720-26-7)

Safety Data

• Hazardous Substances Data: 1615720-26-7(Hazardous Substances Data)

Upstream product

• 2935-35-5 (S)-2-phenylglycine 
• 1208071-35-5 [2-(5-cyano-3-hydroxy-pyridin-2-yl)thiazol-4-yl]acetic acid 
• 573675-25-9 5-bromo-3-nitropyridine-2-carbonitrile 
• 1208071-34-4 [2-(5-cyano-3-hydroxy-pyridin-2-yl)thiazol-4-yl]acetic acid butyl ester 
• 1208071-33-3 [2-(5-bromo-3-hydroxy-pyridin-2-yl)thiazol-4-yl]acetic acid butyl ester 
• 1208071-32-2 5-bromo-3-hydroxy-pyridine-2-carbothioic acid amide 
• 36057-46-2 5-bromo-3-methoxy-pyridine-2-carbonitrile 

Relevant articles and documents

Discovery of novel 2-[2-(3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetamide derivatives as HIF prolyl 4-hydroxylase inhibitors; SAR, synthesis and modeling evaluation

The design, synthesis, and capacity to inhibit HIF prolyl 4-hydroxylases (PHDs) are described for 2-[2-(3-hydroxy-pyridin-2-yl)-thiazol-4-yl]-acetamide analogs. These analogs revealed two kinds of novel scaffolds as PHD2 inhibitors. Synthetic routes were