1615737-65-9

Basic information

• Product Name: N¹-(3,5-bis(trifluoromethyl)phenyl)-N²-(3-hydroxyphenyl)phthalamide
• Synonyms: N¹-(3,5-bis(trifluoromethyl)phenyl)-N²-(3-hydroxyphenyl)phthalamide
• CAS NO: 1615737-65-9
• Molecular Weight: 468.355
• Mol File: 1615737-65-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N¹-(3,5-bis(trifluoromethyl)phenyl)-N²-(3-hydroxyphenyl)phthalamide(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-(3,5-bis(trifluoromethyl)phenyl)-N²-(3-hydroxyphenyl)phthalamide(1615737-65-9)
• EPA Substance Registry System: N¹-(3,5-bis(trifluoromethyl)phenyl)-N²-(3-hydroxyphenyl)phthalamide(1615737-65-9)

Safety Data

• Hazardous Substances Data: 1615737-65-9(Hazardous Substances Data)

Upstream product

• 1253889-39-2 3-(3,5-bis(trifluoromethyl)phenylimino)isobenzofuran-1(3H)-one 
• 591-27-5 m-Hydroxyaniline 
• 24063-31-8 2-(3,5-bis(trifluoromethyl)phenylcarbamoyl)benzoic acid 
• 85-44-9 phthalic anhydride 
• 328-74-5 3,5-Bis-(trifluoromethyl)aniline 

Relevant articles and documents

Enantioselective synthesis of 1-vinyltetrahydroisoquinolines through palladium-catalysed intramolecular allylic amidation with chiral PhthalaPhos ligands

The PhthalaPhos ligands, chiral BINOL monophosphites endowed with a phthalamide group, have been screened in the synthesis of 1- vinyltetrahydroisoquinolines by intramolecular palladium-catalysed asymmetric allylic amidation (AAA) of achiral tosylamidocarbonates. Identification of the best ligand followed by optimisation of the reaction conditions allowed the desired product to be obtained with up to 83% ee. Remarkably, the reaction is stereoconvergent, affording the same enantiomer of the desired product regardless of the geometry of the allylic carbonate's double bond, which allows, in principle, the use of E/Z mixtures.