1616883-32-9

Basic information

• Product Name: 5-[4'-methoxybenzylsulfanyl]-O^2',O^3',O^5',N⁴-tetrapivaloylcytidine
• CAS NO: 1616883-32-9
• Molecular Weight: 731.908
• Mol File: 1616883-32-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[4'-methoxybenzylsulfanyl]-O^2',O^3',O^5',N⁴-tetrapivaloylcytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4'-methoxybenzylsulfanyl]-O^2',O^3',O^5',N⁴-tetrapivaloylcytidine(1616883-32-9)
• EPA Substance Registry System: 5-[4'-methoxybenzylsulfanyl]-O^2',O^3',O^5',N⁴-tetrapivaloylcytidine(1616883-32-9)

Safety Data

• Hazardous Substances Data: 1616883-32-9(Hazardous Substances Data)

Upstream product

• 3066-86-2 5-bromocytidine 
• 3282-30-2 pivaloyl chloride 
• 65-46-3 CYTIDINE 
• 1616883-23-8 5-bromo-O^2′,O^3′,O^5′,N⁴-tetrapivaloylcytidine 
• 6258-60-2 p-methoxybenzylmercaptan 

Relevant articles and documents

A general approach to the synthesis of 5-S-functionalized pyrimidine nucleosides and their analogues

A general and efficient approach was developed for the introduction of S-functionality at the C-5 position of cytosine and uracil nucleosides and their analogues. The key step is a palladium-catalyzed C-S coupling of the corresponding 5-bromo nucleoside derivative and alkyl thiol. The butyl 3-mercaptopropionate coupling products were further converted to the corresponding disulphides, the stable precursors of 5-mercaptopyrimidine nucleosides. the Partner Organisations 2014.