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16188-30-0

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16188-30-0 Usage

Description

1,3-Thiazol-4-ylmethylamine is an organic compound with the molecular structure containing a thiazol ring and an amine group. It is a versatile building block in the synthesis of various pharmaceutical compounds due to its unique chemical properties and reactivity.

Uses

Used in Pharmaceutical Industry:
1,3-Thiazol-4-Ylmethylamine is used as a reactant for the preparation of quinazoline antifolate thymidylate synthase inhibitors. It plays a crucial role in the development of these inhibitors by replacing glutamic acid, which contributes to their enhanced efficacy in targeting and inhibiting the enzyme responsible for DNA synthesis and cell proliferation in cancer cells. This application is particularly relevant in the development of novel anticancer drugs and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 16188-30-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,1,8 and 8 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16188-30:
(7*1)+(6*6)+(5*1)+(4*8)+(3*8)+(2*3)+(1*0)=110
110 % 10 = 0
So 16188-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2S/c5-1-4-2-7-3-6-4/h2-3H,1,5H2

16188-30-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,3-thiazol-4-ylmethanamine

1.2 Other means of identification

Product number -
Other names Thiazol-4-ylmethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16188-30-0 SDS

16188-30-0Relevant articles and documents

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Jones et al.

, p. 4526,4528 (1950)

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