161891-26-5

Basic information

• Product Name: 2-Propenal, 3-chloro-3-(4-methoxyphenyl)-, (E)-
• CAS NO: 161891-26-5
• Molecular Formula: C10H9ClO2
• Molecular Weight: 196.633
• Mol File: 161891-26-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 3-chloro-3-(4-methoxyphenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 3-chloro-3-(4-methoxyphenyl)-, (E)-(161891-26-5)
• EPA Substance Registry System: 2-Propenal, 3-chloro-3-(4-methoxyphenyl)-, (E)-(161891-26-5)

Safety Data

• Hazardous Substances Data: 161891-26-5(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 37572-24-0 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylic acid ethyl ester 

Downstream Products

• 1620397-64-9 (E)-3-(4-methoxyphenyl)-3-(methylthio)acrylaldehyde 
• 28592-29-2 2-carbethoxy-5-(4-methoxyphenyl)pyrrole 
• 130445-93-1 3-cyano-2-methyl-6-(4-methoxyphenyl)pyridine 
• 4385-63-1 2-(4-methoxyphenyl)-6-methyl-pyridine 
• 869709-83-1 4-Chloro-6-(4-methoxyphenyl)thieno[3,2-d] pyrimidine 
• 225385-22-8 6-(4-Methoxyphenyl)thieno[3,2-d] pyrimidin-4(3H)-one 
• 1610410-52-0 Ethyl 3-formamido-5-(4-methoxyphenyl)thiophene-2-carboxylate 
• 37572-24-0 3-amino-5-(4-methoxyphenyl)thiophene-2-carboxylic acid ethyl ester 
• 887247-33-8 3-Chloro-3-(4-methoxyphenyl)acrylonitrile 

Relevant articles and documents

Synthesis of novel β-aryl-β-(methylthio)acroleins via Vilsmeier-Haack protocol as potential 1,3-dielectrophilic three-carbon building blocks

A new general route for the synthesis of novel β-aryl-β- (methylthio)acroleins, a class of stable potential 1,3-dielectrophilic synthons, has been reported. The overall protocol involves treatment of either β-chloroacroleins or their precursor iminium salts (generated in situ from the corresponding active methylene ketones under Vilsmeier-Haack reaction conditions) with S,S-dimethyldithiocarbonates (DDC)/aqueous KOH in either a one-pot or two-step process. The dimethyldithiocarbonate (DDC)/30% aqueous KOH has been shown to be an excellent source of methylthiolate anion.

The application of unsymmetrical vinylogous iminium salts and related synthons to the preparation of monosubstituted triazolo[1,5-a]pyrimidines

The reaction of vinylogous iminium salts and related analogs with 3-amino-1,2,4-triazole to yield 7-substituted and 5-substituted triazolo[1,5-a]pyrimidines is described.