16212-06-9

Basic information

• Product Name: PHENYL TRANS-STYRYL SULFONE
• Synonyms: BUTTPARK 44\07-07;PHENYL TRANS-STYRYL SULFONE;PHENYL TRANS-STYRYL SULPHONE;TRANS-PHENYL BETA-STYRYLSULFONE;-styrylsulfone;trans-Phenyl §trans-Phenyl styrylsulfone, 98%;trans-phenyl á-styrylsulfone
• CAS NO: 16212-06-9
• Molecular Formula: C₁₄H₁₂O₂S
• Molecular Weight: 244.31
• Mol File: 16212-06-9.mol
• Article Data: 125

Chemical Properties

• Melting Point: 74-75 °C(lit.)
• Boiling Point: 438.2 °C at 760 mmHg
• Flash Point: 275.1 °C
• Appearance: /
• Density: 1.221 g/cm³
• Vapor Pressure: 1.81E-07mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: PHENYL TRANS-STYRYL SULFONE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYL TRANS-STYRYL SULFONE(16212-06-9)
• EPA Substance Registry System: PHENYL TRANS-STYRYL SULFONE(16212-06-9)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• Hazardous Substances Data: 16212-06-9(Hazardous Substances Data)

Usage

Uses

Phenyl trans-beta-styryl sulfone is used as a building block for proteomics research.

Synthesis Reference(s)

Synthetic Communications, 19, p. 2209, 1989 DOI: 10.1080/00397918908052616Tetrahedron Letters, 25, p. 3203, 1984 DOI: 10.1016/S0040-4039(01)91008-1

InChI:InChI=1/C14H12O2S/c15-17(16,14-9-5-2-6-10-14)12-11-13-7-3-1-4-8-13/h1-12H/b12-11-

Upstream product

• 51755-92-1 β-phenyl-β-hydroxyethyl phenyl sulfone 
• 52147-97-4 trans 2-phenylethenesulfonyl chloride 
• 3959-23-7 benzenesulfonylacetic acid 
• 100-52-7 benzaldehyde 
• 108-98-5 thiophenol 
• 536-74-3 phenylacetylene 
• 100-42-5 styrene 
• 873-55-2 sodium benzenesulfonate 
• 67-56-1 methanol 
• 32291-77-3 phenyl (Z)-β-styryl sulphone 
• 108-86-1 bromobenzene 
• 88486-41-3 1-(tri-n-butylstannyl)-2-(phenylsulfonyl)ethene 
• 27846-25-9 1-phenyl-2-(phenylsulfonyl)ethane 
• 591-50-4 iodobenzene 

Downstream Products

• 69333-48-8 1-phenyl sulphonyl-2-methoxy-2-phenyl ethane 
• 27846-25-9 1-phenyl-2-(phenylsulfonyl)ethane 
• 65885-18-9 phenyl (2-phenyl-2-ethoxy ethyl)sulphone 
• 65885-20-3 (2-benzenesulfonyl-1-phenyl-ethyl)-dimethyl-amine 
• 21309-15-9 trans-2-phenyl-phenylsulfonyl cyclopropane 
• 39542-24-0 4-(2-benzenesulfonyl-3-phenyl-cyclopropanesulfonyl)-morpholine 
• 128593-04-4 1-phenyl-2-(benzenesulphonyl)-1-(1-pyrrolidyl)ethane 
• 128593-05-5 1-phenyl-2-(benzenesulphonyl)-1-(1-piperidyl)ethane 
• 87289-94-9 (3R,4R,5S)-4-Benzenesulfonyl-2,3,5-triphenyl-isoxazolidine 
• 55930-68-2 2-(1-Phenylsulfonyl-2-phenylaethyl)cyclohexanon 
• 344564-13-2 2-(1-Phenyl-2-phenylsulfonylaethyl)cyclohexanon 
• 82884-24-0 3-Benzenesulfonyl-2,6-diphenyl-2,3,4,7-tetrahydro-1H-azepine 
• 16037-44-8 4-phenyl-3-trimethylsilylpyrazole 
• 3846-66-0 (E)-1-tert-butyl-2-phenylethene 

Relevant articles and documents

-

-

Facile method for solid-phase synthesis of vinyl sulfones using polystyrene-supported selenomethyl aryl sulfone

Treatment of novel polystyrene-supported selenomethyl aryl sulfone with LDA followed by alkylation and oxidation elimination efficiently afforded vinyl sulfones in good yields and purities.

Visible-Light-Induced Three-Component Intermolecular Trifluoromethyl-Alkenylation Reactions of Unactivated Alkenes

Herein, we describe a practical protocol for efficient, mild, visible-light-induced three-component intermolecular trifluoromethyl-alkenylation reactions of unactivated alkenes. The protocol has good functional group tolerance and a broad substrate scope. Using this protocol, we not only introduced a trifluoromethyl group into alkenes but also converted unactivated alkenes to styrene-based activated alkenes, in addition to accomplishing late-stage functionalization of pharmaceutical intermediates. (Figure presented.).

Selective synthesis of sulfoxides and sulfonesviacontrollable oxidation of sulfides withN-fluorobenzenesulfonimide

A practical and mild method for the switchable synthesis of sulfoxides or sulfonesviaselective oxidation of sulfides using cheapN-fluorobenzenesulfonimide (NFSI) as the oxidant has been developed. These highly chemoselective transformations were simply achieved by varying the NFSI loading with H2O as the green solvent and oxygen source without any additives. The good functional group tolerance makes the strategy valuable.