162467-43-8

Basic information

• Product Name: 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 1,1-dioxide
• Synonyms: 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 1,1-dioxide
• CAS NO: 162467-43-8
• Molecular Weight: 390.373
• Mol File: 162467-43-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 1,1-dioxide(162467-43-8)
• EPA Substance Registry System: 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 1,1-dioxide(162467-43-8)

Safety Data

• Hazardous Substances Data: 162467-43-8(Hazardous Substances Data)

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 621-21-6 (1E,4E)-1,5-bis(3-nitrophenyl)penta-1,4-dien-3-one 
• 162467-33-6 2,3,5,6-Tetrahydro-2,6-di(3-nitrophenyl)thiopyran-4-one 

Downstream Products

• 621-21-6 (1E,4E)-1,5-bis(3-nitrophenyl)penta-1,4-dien-3-one 

Relevant articles and documents

Syntheses of 4H-thiopyran-4-one 1,1-dioxides as precursors to sulfone-containing analogues of tetracyanoquinodimethane

Synthetic routes to the unsubstituted 4H-thiopynan-4-one 1,1-dioxide (5a), 2,6-dialkyl-substituted, 2-aryl- or 2-heteroaryl-6-alkyl-substituted, 2,6-diaryl- or diheteroaryl-substituted, and 2-heteroaryl-6-aryl-substituted 4H-thiopyran-4-one 1,1-dioxides 5b-s are described. Sodium hydrosulfide hydrate in buffered aqueous alcohol can be used as a substitute for hydrogen sulfide gas for the introduction of sulfur to methyl acrylate, to 1,5-disubstituted-1,4-pentadien-3-ones 13, or to 1,5-disubstituted-1,4-pentadiyn-3-ones 17. The double dehydrogenation of 2,3,5,6-tetrahydrothiopyran-4-one 1,1-dioxides 13 with iodine-DMSO-sulfuric acid gives thiopyran-4-one 1,1-dioxides 5 in good yield and small amounts of 1,4-pentadien-3-ones 13. 2,3,5,6-Tetrahydrothiopyran-4-one 1,1-dioxide (9) and 5,6-dihydrothiopyran-4-one 1,1-dioxide (12), which lack aryl or heteroaryl substituents, give poor yields of 4H-thiopyran-4-one 1,1-dioxide (5a) with iodine-DMSO-sulfuric acid.