162549-00-0Relevant articles and documents
N,N-Dimethylformamide as Hydride Source in Nickel-Catalyzed Asymmetric Hydrogenation of α,β-Unsaturated Esters
Guo, Siyu,Zhou, Jianrong
, p. 5344 - 5347 (2016)
Asymmetric transfer hydrogenation of α,β-unsaturated esters is realized by using a nickel/bisphosphine catalyst and N,N-dimethylformamide (DMF) as the hydride source.
Lipase catalysed kinetic resolutions of 3-aryl alkanoic acids
Deasy, Rebecca E.,Brossat, Maude,Moody, Thomas S.,Maguire, Anita R.
scheme or table, p. 47 - 61 (2011/04/18)
Hydrolase catalysed kinetic resolutions leading to a series of 3-aryl alkanoic acids (≥94% ee) are described. Hydrolysis of the ethyl esters with a series of hydrolases was undertaken to identify biocatalysts that yield the corresponding acids with excellent enantiopurity in each case. Steric and electronic effects on the efficiency and enantioselectivity of the biocatalytic transformation were also explored.
Bicyclic amide derivatives and their use as muscle relaxants
-
, (2008/06/13)
Novel compounds of formula (1) together with their salts and solvates have a number of uses in medicine, in particular as central muscle relaxants.
